May 2008

Hepatotoxic and hemolytic effects of acute exposure of rats to artesunate overdose

  Hepatotoxic and hemolytic effects of artesunate overdose were examined in rats. Forty (40) rats were grouped randomly into four designated as A, B, C, and D. and were given oral administration of artesunate as follows: 0 mg/kg (control), 1 mg/kg (Under-dose), 2 mg/kg (Normal dose) and 4 mg/kg (Overdose) respectively.  The administration was continued for 5 days. Hepatotoxicity was monitored in the rats...

Author(s): Omotuyi I. O, Nwangwu S. C, Okugbo O. T, Okoye O. T, Ojieh G. C and Wogu D.M

May 2008

Effect of aerobic pre-treatment on production of hydrolases and volatile fatty acids during anaerobic digestion of solid sisal leaf decortications residues

  The effect of aerobic pretreatment on the production of hydrolases and volatile fatty acids during anaerobic digestion of solid sisal decortications leaf residue (SLDR) was investigated. Batch solid waste bioreactors with working volume of 2 litres were used in this study.  Batch loads of aerobically treated or untreated sisal leaf residue inoculated with activated sludge mixed culture were packed into...

Author(s): Anthony Manoni Mshandete, Lovisa Björnsson, Amelia Kajumulo Kivaisi, Mugassa Steven Thomas Rubindamayugi and Bo Mattiasson

May 2008

A comparative study on the atheroprotective potential of heparin and atorvastatin in hypercholesterolemic rats

  The present study is to evaluate the effect of standard drug heparin and atorvastatin on the atherogenic disturbances in hypercholesterolemic atherogenic animals. Six groups of male Wistar rats were employed in this study, of which three groups received atherogenic CCT diet (rat chow supplemented with 4% cholesterol, 1% cholic acid and 0.5% thiouracil) for 17 days. Two groups were treated with...

Author(s): Vijayabaskar P, Sethupathy S and Somasundaram S. T