African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007

AJBR Articles in press

Study of isoforms of nicotinamide adenine dinucleotide phosphate oxidase of the heart in a model of rats fed on several vegetable oils.

Article in Press

Palm oil has long been incriminated in obesity, and this obesity would be responsible for the development of cardiac fibrosis, several authors have evoked the role of free radicals in the pathophysiological mechanism of the fibrotic response linked to obesity; The aim of this study was therefore to evaluate the profile of NOX2 in the development of cardiac fibrosis in rats subjected to a diet rich in the fat of several...


Dynamics of Ascaridigalli infection and serum retinol level following supplementation with Vitamin A

Article in Press

The present study was conducted to assess the effect of Ascaridia galli infection on vitamin A supplementation and serum retinol concentrations. These were assessed in 100 eight weeks ISA brown chickens experimentally infected with A. galli. The chickens were divided into four equal groups (G1, G2, G3 and G4) of ten chickens (n=10). The chickens were experimentally infected with 350 eggs of A. galli and daily supplemented...

Author(s):George Gaymary Bakari, Elifuraha Barnabas Mngumi, Robert Arsen Max and Amandus Muhairwa

Some physicochemical Properties of a 49.7 kDa Glutathione Transferase from African Palm Weevil (Rhynchophorus Phoenicis) Larvae

Article in Press

Glutathione transferase is a mutigene family of enzymes catalyzing the conjugation of glutathione with a large variety of xenobiotics. Glutathione transferase acts on different substrates and can protect insects against various plant allelochemicals and chemical insecticides. An investigation of glutathione transferase in the gut of Palm weevil (Rhynchophorus phoenicis) larva, a lethal pest of palm was carried out. This...

Author(s):Bamidele O. Samuel, Ajele J. Oluwafemi

Ascorbic acid attenuates hematological and hepatic derangements in rats co-treated with Atrazine and sodium nitrate

Article in Press

The present study examined the roles of ascorbic acid (AA) on hematological indices, hepatic function and lipid profile, and liver histology in rats co-treated with Atrazine (ATZ) and sodium nitrate (NaNO3). The hematological indices, liver function tests, lipid profile, and liver histology were performed using standard protocols. The [ATZ + NaNO3] significantly (p < 0.05) reduced the levels of hemoglobin, red blood cells,...

Author(s):Adeleke Gbadebo Emmanuel, O.K. Raheem, Adedosu, Olaniyi Temitope, Fatoki John Olabode

Tamoxifen treatment improves serum lipid profile with possible cardio-protective effect.

Article in Press

Breast cancer is the most widely recognized cancer in women worldwide and it is the main source of cancer demise in less created nations. Dyslipidemia in breast cancer patients has been considered as a hazard factor for cardiovascular diseases. Tamoxifen is basically hostile to estrogenic and its estrogenic action is fundamentally liable for the adjustments in lipid parameters. Investigation of lipid profiles among breast...

Author(s):Solomon Genet,Bihonegn Berhan, Wondemagegnehu Tigeneh, Tigistu Gebretensaye


Article in Press

Carissa edulis and Caesalpinia volkensii have been used through ages by herbalists in many parts of the world to treat various ailments. Although these medicinal plants have been widely used traditionally in treating diseases associated with oxidative stress, there is limited literature to validate their use. This study therefore, sought to determine the ethnobotanical efficacy of the plants as alternatives in the...

Author(s):Kibiwott Jepkorir Scolar, Ng’ang’a Mwihaki Margaret, and Ngugi Mathew Piero

A comparative study on determination of selected essential and heavy metals from Avocado, Mango and Banana with their supporting soil samples cultivated in Yeki Woreda, Southwest Ethiopia

Article in Press

The study was focused on the quantitative determination of some selected essential and heavy metals in avocado, banana and mango samples with their respective supported soil samples collected from 8 kebeles of Yeki woreda. The investigated metals were Ca, Cd, Cr, Cu, Ni, Pb and Zn. Acid digestion was used for sample digestion. Flame atomic absorption spectrometer (FAAS) was used to determine the concentration of metals....

Author(s):Berhe Akele, Shisho Haile


Article in Press

The global malaria control and elimination strategies are constrained by the emergence and spread of multi-drug resistant Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae strains to most antimalarials. Currently, studies reveal rising incidences of reduced parasite susceptibility to the artemisinin-based combination therapies (ACTs), the recommended first-line treatment regimen for uncomplicated P....

Author(s):Milka Wambui, Daniel Wainaina Kariuki, Johnson Kang’ethe Kinyua, Francis Thuo Kimani and Joseph Kang’ethe Ng’ang’a

Acute oral toxicity study of Acacia nilotica bark of aqueous methanolic extract in albino mice

Article in Press

The beneficial use of medicinal plant among rural communities has been reported over century’s medicinal properties and toxicity of the plant varies depending on the part of the plant taken like leaves, roots, stem and bark as well as geographical distribution, climate change and nature of the soil. This study aimed to assess the acute toxicity of Tanzania Acacia nilotica extracts in mice. The information generated is...

Author(s):Raphael Mwezi, Revocutus L Machunda, Hamisi M Malebo

In vivo antimalarial activity of bark extracts of Lannea acida (anacardiaceae) and chloroquine against Plasmodium berghei in mice.

Article in Press

Lannea acida plants belong to the family Anacardiaceae. It has been used locally to treat and manage diseases that are contagious. Due to the recent increase in the resistance of malaria parasite to synthetic drugs the search for alternative treatment approach from plant sources is in urgent dimension. The antiplasmodial activity of mice was investigated with L. acida bark extracts. The study of the acute toxicity of the...

Author(s):Olusola A. O, Ogunsina O.I., Ayedogbon S.O, Olusola, A.O

Cardioprotective effect of methanolic extract of Magnifera indica (mango) seed flour on acetaminophen-induced cardiotoxicity in albino rats

Article in Press

This study evaluated the effect of methanol extract of mango (Magnifera indica) seed flour on acetaminophen-induced cardiotoxicity in albino rats. Twenty four (24) male and female albino rats were divided into 6 groups consisted of 4 rats: a)Group1: Control group (no induction and treated with distilled water only);b) Group 2 (acetaminophen-induced and untreated); c) Group 3 (acetaminophen-induced and pre-treated with...

Author(s):Nkwocha, Chinelo Chinenye

Improvement and validation of 96 well-microtiter plate-ABTS based assay for estimation of antioxidant activity in green leafy vegetables

Article in Press

The objective of our study was to develop 96 well-microtiter plate 2, 2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) based decolorization assay method for analysis of large number of samples in a single run for the screening of antioxidant activity of various extracts such as food extracts, plasma antioxidants and synthetic antioxidants and optimization was carried out for parameters like concentration,...

Author(s):Meera I, Sivakumar ChV, Tekeba Sisay

Changes in Lipid Class and Fatty Acid Composition during the Development of African pear (Dacryodes edulis) fruit pulp

Article in Press

The pulp of the African pear (D.edulis) fruits were investigated for its oil compositions, major lipid classes and constituents fatty acids from 4 weeks after anthesis (WAA) to fruit maturation. The oil was extracted with n-hexane using soxhlet extractor and characterised by gas chromatography. Fatty acid profile showed a saturated acid content of between 19.5-36.5% and unsaturated fatty acid content of 63.5-80.5%....

Author(s):Uhunmwangho E.S. and Omoregie E.S.


Article in Press

This study focused on the integrity retention profile of hematological disorder indices on exposure to ethanol extract of Corchorus olitorus leaf. Seventy two apparently healthy rats were obtained from the animal farm of the Department of Zoology and Environmental Biology University of Nigeria, Nsukka and used for this study. These indices include assessed were Red blood cell distribution width standard deviation, Red...


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