Abstract
Aim: To evaluate the haematological, biochemical and histological effects of palm bunch ash (PBA) and trona when used as tenderizers.
Methods: Thirty male albino rats were randomly grouped into five designated 1(control), 2, 3, 4 and 5, and were orally given 2 ml of distilled water, 486 mg/kg of trona, 972 mg/kg of Trona, 486 mg/kg of PBA, 972 mg/kg of PBA, respectively for 21 days.
Results: The study showed decreased body and liver weights (195.00 ± 20.50 to 152.80 ± 27.81{p<0.05} and 9.13 ± 1.28 to 7.38 ± 1.59 {p>0.05}, respectively) and higher relative weight (4.68 ± 0.98 to 4.83 ± 0.34 {p>0.05}) and serum levels of alkaline phosphatase (165.83 ± 16.73 to 349.67 ± 201.99 {p>0.05}). Significant differences in lactate dehydrogenase activity (p<0.05) and insignificant differences in the estimated haemoglobin, packed cell volume, serum amylase and transaminases were also observed (p>0.05). Liver microscopy in the test groups revealed evidences of hepatitis and cholestasis.
Conclusion: this study suggests that both trona and PBA are more toxic at 972 mg/kg but less toxic at 486 mg/kg body weight. Thus, lower concentrations are advised when used as tenderizing agents.
Key words: Trona, Palm bunch ash, Tenderizer, enzymes
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