July 2016

EFFECT OF PRENATAL ETHANOL EXPOSURE AND EXTRACT OF TAMARINDUS INDICA PULP ON THE CEREBRAL CORTEX OF WISTAR RATS

Aim: The aim of the study was to evaluate the effect of ethanolic pulp extract of Tamarindus indica (EPTI) on the cerebral cortex in prenatal ethanol exposure in Wistar rats. Method: Twenty four pregnant rats were divided into 7 groups. The Control received 1ml of water, Groups 2 and 3 received 200mg/kg and 300mg/kg body weight (bw) of EPTI and Vitamin E respectively, Group 4 received 0.1ml of olive oil, Group 5...

Author(s): Usman IM, Buraimoh AA, Ibegbu AO  

July 2016

HEMATOLOGICAL EVALUATION OF ABINO RATS ORALLY ADMINISTERED PYRETHROIDS FORMULATION

Aim: This study was carried out to determine the effect of Mortein on some hematological parameters. Methods: Fifty adult Albino rats (150- 200g) were acquired from the animal house of the College of Health Sciences, Delta State University Abraka and placed into four groups. Groups 1- 3 contained 15 rats each, while 4 contained 5 rats. Groups 1-3 were further sub-divided into 3 sub-groups of 5 rats each. The rats in...

Author(s): Iteire AK  

July 2016

COGNITIVE-ENHANCING AND NEUROTHERAPEUTIC PROSPECTS OF VISCUM ALBUM IN EXPERIMENTAL MODEL OF ALZHEIMER’S DISEASE

Aim: Histomorphological effect of ascorbic acid on mercury exposure on temporal lobe of the cerebral cortex of Adult Wistar rats was investigated. Methods: Twenty five adult Wistar rats of average weight of 185 grams were randomly divided into five groups of five rats per group namely; a control group administered with normal saline, a mercuric chloride only group (HgCl2; 49.8mg/kg), HgCl2 with distilled water...

Author(s): Animoku AA, Mesole SB, Yusuf UA, Ayuba M

July 2016

COGNITIVE-ENHANCING AND NEUROTHERAPEUTIC PROSPECTS OF VISCUM ALBUM IN EXPERIMENTAL MODEL OF ALZHEIMER’S DISEASE

Aim: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by multiple cognitive deficits, behavioural disorders, mood changes and neurohistological alterations including neurofibrillary degeneration, and development of plaques and tangles of fibrous proteins in the brain. Novel natural antioxidants from plants like Viscum album may offer an effective and safe means of bolstering the...

Author(s): Oremosu Ademola, Edem Edem, Dosunmu Olufunke, Kunlere Oladunni