African Journal of
Food Science

  • Abbreviation: Afr. J. Food Sci.
  • Language: English
  • ISSN: 1996-0794
  • DOI: 10.5897/AJFS
  • Start Year: 2007
  • Published Articles: 896

Full Length Research Paper

Health risk assessment of Brazil nut consumption by aflatoxin biomarker in urine samples

Ariane Kluczkovski
  • Ariane Kluczkovski
  • Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Brazil.
  • Google Scholar
Augusto Kluczkovski-Junior
  • Augusto Kluczkovski-Junior
  • Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Brazil.
  • Google Scholar
Samia Braga
  • Samia Braga
  • Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Brazil.
  • Google Scholar
Emerson Lima
  • Emerson Lima
  • Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Brazil.
  • Google Scholar
Cibele Viana
  • Cibele Viana
  • Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Brazil.
  • Google Scholar
Lawrence Xavier
  • Lawrence Xavier
  • Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Brazil.
  • Google Scholar


  •  Received: 23 March 2020
  •  Accepted: 21 May 2020
  •  Published: 30 June 2020

References

Ali N, Blaskewicz M, Hossain K, Degen GH (2017). Determination of aflatoxin M1 in urine samples indicates frequent dietary exposure to aflatoxin B1 in the Bangladeshi population. International Journal of Hygiene and Environmental Health 220:271-281.
Crossref

 

Bando E, Gonçales LN, Tamura NK, Machinski Junior M (2007). Biomarkers for assessment of human exposure to mycotoxins. Jornal Brasileiro de Patologia e Medicina Laboratorial 43:175-180.
Crossref

 
 

Baquião AC, Zorzete P, Reis, TA, Assunção E, Vergueiro S, Correa B (2012). Mycoflora and myotoxins in Field samples of Brazil nuts. Food Control 28:224-229.
Crossref

 
 

Beltran E, Ibanez M, Sancho JV, Cortes MA, Yusa V, Hernandez F (2011). UPLC-MS/MS highly sensitive determination of aflatoxins, the aflatoxin metabolite M1 and ochratoxin A in baby food and milk. Food Chemistry 126:737-744.
Crossref

 
 

Becker-Algeri TA, Castagnaro D, de Bortoli K, De Souza C, Drunkler DA, Badiaçle-Furlong E (2016). Mycotoxins in Bovine Milk and Dairy Products: A Review. Journal of Food Science 81(3):R544-5552.
Crossref

 
 

Benkerroum N (2019). Retrospective and Prospective Look at Aflatoxin Research and Development from a Practical Standpoint. International Journal of Environmental Research and Public Health 16:363.
Crossref

 
 

Bui-Klimke TR, Wu F (2015). Ochratoxin A and human health risk: A review of the evidence. Critical Reviews in Food Science and Nutrition 55(13):1860-1869.
Crossref

 
 

Chen C, Mitchell, NJ, Gratz J, Houpt ER, Gong Y, Egner PA, Groopman JD, Riley RT, Showker JL, Svensen E, Mduma ER, Patil CL, Wu F (2018). Exposure to aflatoxin and fumonisin in children at risk for growth impairment in rural Tanzania. Environment International 115:29-37.
Crossref

 
 

European Food Safety Authority (EFSA) (2005). Opinion of the Scientific Committee on a request from EFSA related to a harmonized approach for risk assessment of substances which are both genotoxic and carcinogenic [Internet]. EFSA Journal.

 
 

Fay MP, Proschan MA (2010). Wilcoxon-Mann-Whitney or t-test? On assumptions for hypothesis tests and multiple interpretations of decision rules. Statistics Surveys, Institute of Mathematical Statistics 4:1-39.
Crossref

 
 

Genest C, Neslehova JG, Remillard B (2013). On the estimation of Spearman's rho and related tests of independence for possibly discontinuous multivariate data. Journal of Multivariate Analysis 117: 214-228.
Crossref

 
 

He Y, Fang J, Peng X, Cui H, Zuo Z, Deng J, Chen Z, Geng Y, Lail W, Hatch MC, Chen CJ, Levin B, Ji BT, Yang GY, Hsu SW, Wang LW, Hsieh LL, Santella RM (1993a). Urinary aflatoxin levels, hepatitis‐B virus infection and hepatocellular carcinoma in Taiwan. International Journal of Cancer 54(6):931-934.
Crossref

 
 

Hatch MC, Chen CJ, Levin B (1993b). Urinary aflatoxin levels, hepatitis-B virus infection and hepatocellular carcinoma in Taiwan. International Journal of Cancer 54:931-934.
Crossref

 
 

Heshmati A, Milani JM (2010). Contamination of UHT milk by aflatoxin M1 in Iran. Food Control 21:19-22.
Crossref

 
 

International Agency for Research on Cancer (IARC) (1993). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, v. 56. Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic Aromatic Amines and Mycotoxins. IARC Press, Lyon.

 
 

Institute of Medicine (IOM) (2001). Food Safety Policy, Science, and Risk Assessment: Strengthening the Connection. Workshop Proceedings. Food Forum, Food and Nutrition Board. National Academy Press, Washington, DC.

 
 

Jardim ANO, Caldas E (2009) Chemical Dietary Exposure and the risks to human health. Quim. Nova 32(7):1898-1909.
Crossref

 
 

Jager AV, Tonin FG, Baptista GZ, Souto RT, Oliveira CAF (2016). Assessment of aflatoxin exposure using serum and urinary biomarkers in São Paulo, Brazil: A pilot study. International Journal of Hygiene and Environmental Health 219(3):294-300.
Crossref

 
 

Jager AV, Tonin FG, Baptista GZ, Souto RT, Oliveira CAF (2014). Determination of Urinary Biomarkers for Assessment of Short-Term Human Exposure to Aflatoxins in São Paulo, Brazil. Toxins 6:1996-2007.
Crossref

 
 

Jonsyn-Ellis FE (2000). Seasonal variation in exposure frequency and concentration levels of aflatoxin and ochratoxins in urine samples of boys and girls. Mycopathologia 152:35-40.
Crossref

 
 

Kruschke JK (2014). Doing Bayesian data analysis: A tutorial with R, JAGS, and Stan. 2. ed. Londres: Academic.

 
 

Leong Y, Rosmab A, Aishah A, Latiff A, Izzah N (2012). Associations of serum aflatoxin B1-lysine adduct level with socio-demographic factors and aflatoxins intake from nuts and related nut products in Malaysia. International Journal of Hygiene and Environmental Health 215:368-372.
Crossref

 
 

Limaye A, Yu R, Chou C, Liu J, Cheng K (2018). Protective and Detoxifying Effects Conferred by Dietary Selenium and Curcumin against AFB1-Mediated Toxicity in Livestock: A Review. Toxins 10:25.
Crossref

 
 

Majeed S, De Boevre M, De Saeger S, Rauf W, Tawab A, Habib F, Rahman M, Iqbal, M (2018). Multiple Mycotoxins in Rice: Occurrence and Health Risk Assessment in Children and Adults of Punjab, Pakistan. Toxins 10(2):77.
Crossref

 
 

Moreira MF, Oliveira TR, Vieira IGP, Freire FCO, Silva SC, Ribeiro LM (2016). Occurrence of fungi and aflatoxins B in nuts and products marketed the Brazilian northeastern regions. Revista do Instituto Adolfo Lutz 75:1698.

 
 

Nugraha A, Khotimah K, Rietjens IMCM (2018). Risk assessment of aflatoxin B1 exposure from maize and peanut consumption in Indonesia using the margin of exposure and liver cancer risk estimation approaches. Food and Chemical Toxicology 113:134-144.
Crossref

 
 

Pacheco AM, Scussel VM (2009). Aflatoxins evaluation on in-shell and shelled dry Brazil nuts for export analyzed by LC-MS/MS-2006 and 2007 harvests. World Mycotoxin Journal 2:295-304.
Crossref

 
 

Qian GS, Ross RK, Yu MC, Yuan JM, Gao YT, Henderson BE, Wogan GN, Groopman JD (1994). A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China. Cancer Epidemiology, Biomarkers and Prevention 3:3-10.

 
 

Redzwan SM, Rosita J, Sokhini AMM, Aquilah ARN (2012). Association Between Aflatoxin M1 Excreted in Human Urine Samples with the Consumption of Milk and Dairy Products. Bulletin of Environmental Contamination and Toxicology 89(6):1115-1119.
Crossref

 
 

Reis TA, Oliveira TD, Baquião AC, Gonçalves SS, Zorzete P, Correa B (2012). Mycobiota and mycotoxins in Brazil nut samples from different states of the Brazilian Amazon region. International Journal of Food Microbiology 159:61-68.
Crossref

 
 

Romero CA, Ferreira TRB, Dos Santos Dias CT, Calori-Domingues MA, Da Gloria E M (2010). Occurrence of AFM1 in urine samples of a Brazilian population and association with food consumption. Food Control 21:554-558.
Crossref

 
 

Schleicher RL, McCoy LF, Powers CD, Sternberg MR, Pfeiffer CM (2013). Serim concentrations of an aflatoxin-albumin adduct in the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Clinica Chimica Acta 423:46-50.
Crossref

 
 

Strunz CC, Oliveira TV, Vinagre JC, Lima A, Cozzolino S, Maranhao RC (2008). Brazil nut ingestion increased plasma selenium but had minimal effects on lipids, apolipoproteins, and high-density lipoprotein function in human subjects. Nutrition Research 28(3):151-155.
Crossref

 
 

Thomson CD, Chisholm A, McLachlan SK, Campbell JM (2008) Brazil nuts: an effective way to improve selenium status. The American Journal of Clinical Nutrition 87(2):379-84.
Crossref

 
 

Vargas EA, Santos EA, Whitaker TB, Slate AB (2011). Determination of aflatoxin risk components for in-shell Brazil nuts. Food Additives and Contaminants Part A 28:1242-1260.
Crossref

 
 

Zhu JQ, Zhang LS, Hu X, Xiao Y, Chen, JS, Xu YC, Fremy J, Chu FS (1987). Correlation of dietary aflatoxin B1 levels with excretion of aflatoxin M1 in human urine. Cancer Research 47:1848-1852.