March 2019

Purification and characterisation of a novel broad spectrum anti-tumor L-glutaminase enzyme from marine Bacillus subtilis strain JK-79

L-glutaminase is a therapeutic enzyme used in the treatment of acute lymphoblastic leukemia (ALL). In this study, the extracellular L-glutaminase produced by Bacillus subtilis strain JK-79 was purified to homogeneity. The purified L-glutaminase has specific activity of 937 U mg−1 with KM and VMax value of 8 × 10-2 mM and 200 µM/ml min, respectively. Sodium dodecyl sulfate polyacrylamide gel...

Author(s): Jambulingam Kiruthika and Sudhakar Swathi  

March 2019

Hepatitis C virus infection in patients infected with human immunodeficiency virus in Cotonou, Benin

Screening of Hepatitis C virus (HCV) infection by molecular test is not routinely performed for the care of human immunodeficiency virus (HIV) infected patients in most countries of Sub-Saharan Africa such as Benin. The aim of this study was to assess the extent of HCV infection in patients infected with HIV in Cotonou. This study was conducted from February to June 2017 on HIV infected patients from the National...

Author(s): Sogbo Frederic, Kpossou Aboudou Raïmi, Affolabi Dissou, Lafia Barnabe and Zannou Marcel,