March 2019

Inhibition of Streptococcus mutans (ATCC 25175) biofilm formation on eugenol-impregnated surgical sutures

The use of bioactive compounds as anti-infective coating on biomaterial surfaces has been studied as a tool against microbial adhesion and the establishment of biofilms. The objective of this work was to evaluate the antibacterial activity of eugenol, specifically the ability to interact with cotton suture threads for preventing adhesion and biofilm formation of Streptococcus mutans (ATCC 25175). The minimum inhibitory...

Author(s): Victor Alves Carneiro, Elaine de Fátima Furtado, Rafaela Mesquita Bastos Cavalcante, Maria Laína Silva, Rondinely Lima Silva, Queli Cristina Fidelis and Francisco Eduardo Aragão Catunda Júnior

March 2019

Utility of molecular diagnostic method compared with conventional methods in detection of etiologic agents of central nervous system infections in Rwanda

The incidence of meningoencephalitis in developing countries is high and its diagnosis being inadequate as it is mainly based on conventional methods with a limited diagnostic capacity for bacterial, fungal and viral detection. This results in prescription of a cocktail of antibiotics, antifungal, or anti-viral drugs, since the causative agent is often unknown. There is therefore need for timely and appropriate...

Author(s): Edouard Ntagwabira, Marianne Wanjiru Mureithi, Jean Baptiste Mazarati, Walter Jaoko and Omu Anzala