African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 368


Chemical constituents and biological activities of the genus Zanthoxylum: A review

J. S. Negi1*, V. K. Bisht1, A. K. Bhandari1, P. Singh2 and R. C. Sundriyal1
1Herbal Research and Development Institute, Mandal, Gopeshwar-246401, Uttarakhand, India. 2Department of Chemistry, HNB Garhwal University, Srinagar-246174, Uttarakhand, India.
Email: [email protected]

  •  Accepted: 04 June 2011
  •  Published: 30 October 2011


Zanthoxylum known as “Timoor” is used as mouth fresh, tooth care, spice and in intoxicating of the fishes. The present study deals with documentation of isolated chemical constituents and biological activities of the genus Zanthoxylum. The chemical constituents and essential oil have been isolated and characterized by several analytical methods. Alkaloids and cumarins are the main constituents of the genus. The presence of alkaloids and essential oil, Zanthoxylum possessed several types of biological activities such as larvicidal, anti-inflammatory, analgesic, antinociceptive, antioxidant, antibiotic, hepatoprotective, antiplasmodial, cytotoxic, antiproliferative, anthelminthic, antiviral and antifungal.


Key wordsZanthoxylum, alkaloids, essential oil, biological activities