African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 357

Full Length Research Paper

Preliminary phytochemical and antimicrobial screening of the leaf extract Pilostigma reticulatum (dc) Hochst

Olusola Adeyanju1, Olajide O. Olutayo1*, Afolayan Michael1 and Arifalo K. M.2
1Chemistry Advanced Laboratory, Sheda Science and Technology Complex, P. M. B. 186, Garki, Abuja, Nigeria. 2Department of Chemistry, College of Education, Ikere-Ekiti, Ekiti State, Nigeria.
Email: [email protected]

  •  Accepted: 28 December 2010
  •  Published: 31 March 2011

Abstract

Ethanolic and aqueous extracts of Pilostigma reticulatum (dc) hochst were screened for their antimicrobial activity against Staphylococcus aureus, Streptococcus pyogen, Escherichia coli, Salmonella thypi and Shigella dysentery. The results indicated that the extracts inhibited the growth of one or more test pathogens. The ethanolic extract showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, alkaloids, glycosides, flavonoids, carbohydrates and terpenes. The minimum inhibitory concentration (MIC) ranges from 8.0 x 10to 1 x 10µg/mI.

 

Key words: Medicinal plant, antimicrobial activity, phytochemical screening,Pilostigma reticulatum, pathogens.