Ethanolic and aqueous extracts of Pilostigma reticulatum (dc) hochst were screened for their antimicrobial activity against Staphylococcus aureus, Streptococcus pyogen, Escherichia coli, Salmonella thypi and Shigella dysentery. The results indicated that the extracts inhibited the growth of one or more test pathogens. The ethanolic extract showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, alkaloids, glycosides, flavonoids, carbohydrates and terpenes. The minimum inhibitory concentration (MIC) ranges from 8.0 x 102 to 1 x 104 µg/mI.
Key words: Medicinal plant, antimicrobial activity, phytochemical screening,Pilostigma reticulatum, pathogens.
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