African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 357

Full Length Research Paper

The chemical composition of essential oil from the root of Cissampelos owariensis (p.beauv) and free radical scavenging activities of its extracts

Olajide Olutayo
  • Olajide Olutayo
  • Chemistry Advanced Laboratory, Sheda Science and Technology Complex, Sheda-Abuja, Nigeria
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Orishadipe Abayomi
  • Orishadipe Abayomi
  • Chemistry Advanced Laboratory, Sheda Science and Technology Complex, Sheda-Abuja, Nigeria
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Fatokun Olakunle
  • Fatokun Olakunle
  • Chemistry Advanced Laboratory, Sheda Science and Technology Complex, Sheda-Abuja, Nigeria
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Akande Temitope
  • Akande Temitope
  • Nuclear Technology Centre, National Atomic Energy Commission, Sheda- Abuja, Nigeria
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IIiya Ibrahim
  • IIiya Ibrahim
  • National Institute for Pharmaceutical Research and Development, Idu- Abuja, Nigeria
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  •  Accepted: 10 June 2013
  •  Published: 30 June 2013

Abstract

Air dried root of Cissampelos owariensis (P.Beauv) on steam distillation yielded 0.82% (w/w) of essential oil. Gas chromatography–mass spectrometry (GC-MS) analysis of the oil resulted in the identification of 11 compounds, among which 1H-cyclopropa[a]naphthalene,1a, 2, 3, 5, 6, 7, 7a, 7b-octahydro-1, 1, 7, 7a-tetramethyl-,(1aR-1aa, 7a, 7aa, 7ba) was found to be the most abundant at 39%. The antioxidant features of the 3 extracts (methanol, chloroform, and n-hexane) of the plant were also evaluated by UV-visible spectrophotometer at 517 nm using inhibition of 2, 2 –diphenyl-1-picrylhyrazyl radical (DPPH) and vitamin C as standard. Out of all the extracts evaluated, only the methanolic extract exhibited potent antioxidant activity that was concentration dependent, followed by chloroform extract as compared with vitamin C.

 

Key words: Cissampelos owariensis, diphenyl-1-picrylhyrazyl radical (DPPH), essential oil, free radical scavenging, inhibition.