African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 368

Full Length Research Paper

Phytochemical Profiling of the Hexane fraction of Crassocephalum crepidioides Benth S. Moore leaves by GC-MS

Opeyemi O. Ayodele
  • Opeyemi O. Ayodele
  • Department of Biochemistry, College of Health and Medical Sciences, Benjamin Carson (Snr.) School of Medicine, Babcock University, Ilishan, Nigeria.
  • Google Scholar
Funmilayo D. Onajobi
  • Funmilayo D. Onajobi
  • Department of Biochemistry, College of Health and Medical Sciences, Benjamin Carson (Snr.) School of Medicine, Babcock University, Ilishan, Nigeria.
  • Google Scholar
Omolaja R. Osoniyi
  • Omolaja R. Osoniyi
  • Department of Biochemistry, College of Health and Medical Sciences, Benjamin Carson (Snr.) School of Medicine, Babcock University, Ilishan, Nigeria.
  • Google Scholar


  •  Received: 22 August 2019
  •  Accepted: 14 February 2020
  •  Published: 31 March 2020

References

Adams CD (1963). Compositae. In: Hepper, F. N. (Editor). Flora of West Tropical Africa 2. London, United Kingdom. Crown Agents for Oversea Governments and Administrations 2(2):225-297.

 

Adjatin A, Dansi A, Badoussi E, Loko YL, Dansi M, Gbaguidi F, Sanni A (2013). Phytochemical screening and toxicity studies of Crassocephalum rubens (Juss. ex Jacq.) S. Moore and Crassocephalum crepidioides (Benth.) S. Moore consumed as vegetable in Benin. Journal of Chemical and Pharmaceutical Research 5(6):160-167.

 

Ajibesin KK (2012). Ethnobotanical survey of plants used for skin diseases and related ailments in Akwa Ibom State, Nigeria. Ethnobotany Research & Applications 10:463-522.

 

Aniya Y, Koyama T, Miyagi C, Miyahira M, Inomata C, Kinoshita S, Ichiba T (2005). Free radical scavenging and hepatoprotective actions of the medicinal herb, Crassocephalum crepidioides from the Okinawa Islands. Biological and Pharmaceutical Bulletin 28(1):19-23.
Crossref

 

Arawande JO, Komolafe EA, Imokhuede B. (2013). Nutritional and phytochemical compositions of fireweed (Crassocephalum crepidioides). International Journal of Agricultural Technology 9(2):439-449.

 

Asif M (2016). Mini Review on Important Biological Properties of Benzofuran Derivatives. Journal of Analytical and Pharmaceutical Research 3(2):00050.
Crossref

 

Ayodele OO, Onajobi FD, Osoniyi O (2019). In vitro anticoagulant effect of Crassocephalum crepidioides leaf methanol extract and fractions on human blood. Journal of Experimental Pharmacology 11:99-107.
Crossref

 

Bahar E, Kazi-Marjahan A, Geum-Hwa L, Hwa-Young L, Harun-Or R, Min-Kyung C, Kashi RB, Hyonok Y (2017). β-Cell protection and antidiabetic activities of Crassocephalum crepidioides (Asteraceae) Benth. S. Moore extract against alloxan-induced oxidative stress via regulation of apoptosis and reactive oxygen species (ROS). BMC Complementary and Alternative Medicine 17:179-190.
Crossref

 

Bahar E, Siddika MS, Bashutosh N, Yoon H (2016). Evaluation of In vitro Antioxidant and In vivo Antihyperlipidemic Activities of Methanol Extract of Aerial Part of Crassocephalum crepidioides (Asteraceae) Benth S Moore. Tropical Journal of Pharmaceutical Research 15(3):481-488.
Crossref

 

Bendre RS, Rajput JD, Bagul SD, Karandikar PS (2016). Outlooks on medicinal properties of eugenol and its synthetic derivatives. Natural Products and Chemical Research 4(212):2. 
Crossref

 

Bogning ZC, Olounlade PA, Alowanou GG, Nguemfo EL, Dongmo AB, Azebaze AGB, Hounzangbe-Adote S (2016). In vitro anthelmintic activity of aqueous extract of Crassocephalum crepidioides (Benth.) S. Moore on Haemonchus contortus. Journal of Experimental and Integrative Medicine 6(1):31-37. 
Crossref

 

Burkill HM (1985). The useful Plants of West tropical Africa. Britain, White Friars Press Limited 2:534.

 

Chaitanya MVNL, Dhanabal SP, Rajendran I, Rajan S (2013). Pharmacodynamic and ethnomedicinal uses of weed species in nilgiris, Tamilnadu State, India: A review. African Journal of Agricultural Research 8(27):3505-3527.
Crossref

 

Chia-chung H, Yi-Ping C, Jyh-Horng W, Chi-Chang, H, Sheng YW, Ning-Sun Y, Lie-Fen S (2007). A Galactolipid possesses Novel Cancer Chemo Preventive Effects by Suppressing Inflammatory Mediators and Mouse B16 Melanoma. Cancer Research 67(14):6907-6915.
Crossref

 

Cordier W, Steenkamp V (2011). Herbal remedies affecting coagulation: A review. Pharmaceutical Biology 50(4):443-52. 
Crossref

 

Dairo FAS, Adanlawo IG (2007). Nutritional quality of Crassocephalum crepidioides and Senecio biafrae, Pakistan Journal of Nutrition 6(1):35-39.
Crossref

 

Duke JA (2013). Dr. Duke's Phytochemical and Ethnobotanical Databases. USA: Agricultural Research Service, AGRIS.

 

Duke JA (2016). "Dr. Duke's Phytochemical and Ethnobotanical Databases" (Data set) Ag Data commons. 

 

Fitzgerald DJ, Stratford M, Gasson MJ, Narbad A (2005). Structure-Function Analysis of the Vanillin Molecule and Its Antifungal Properties. Journal of Agriculture and Food Chemistry 53(5):1769-1775.
Crossref

 

Formica JV, Regelson W (1995). Review of Biology of Quercetin and Related Bioflavonoids. Food and Chemical Toxicology 33:1061-1080.
Crossref

 

Handa SS, Khanuja SPS, Longo G, Rakesh DD (2008). Extraction Technologies for Medicinal and Aromatic Plants, (1st ed.), no. 66. Italy: United Nations Industrial Development Organization and the International Centre for Science and High Technology.

 

Henderson RJF (1973). Crassocephalum crepidioides (Benth.) S. Moore in Australia: in invasive species compendium. Proceedings of the Royal society of Queensland 84(4):55-60.

 

Hosseinzadeh Z, Ramazani A, Hosseinzadeh K, Razzaghi-Asl N, Gouranlou F (2017). An Overview on Chemistry and Biological Importance of Pyrrolidinone. Current Organic Synthesis 15(2):166-178.
Crossref

 

Joshi RK (2014). Study on Essential oil composition of the roots of Crassocephalum crepidioides (benth.) S. Moore. Journal of Chilean Chemical Society 59(1): 2363-2365.
Crossref

 

Karmakar S, Goyary D, Dhruva KJ, Johirul I, Chattopadhyay P, Raju PS (2018). Anti-inflammatory, immunomodulatory and antigenotoxic potential of Crassocephalum crepidioides (Benth.) S. Moore methanolic Extract". EC Pharmacology and Toxicology 64:296-315.

 

Khurt MF, Francher MJ, Mckinlay MA, Lennert SD (1984). Virucidal activity of glutaric acid and evidence for dual mechanism action. Antimicrobial agents and chemotherapy 26(6):924-927.
Crossref

 

Kiew R (2009). Additions to the weed flora of Peninsular Malaysia. Malayan Nature Journal 61(2):133-142.

 

Kim Y, Koo K, Koo Y (2010). Platelet anti-aggregation activities of compounds from Cinnamomum cassia. Journal of Medicinal Food 13(5):1069-1074.
Crossref

 

Kostermans AJGH, Wirjahardja S, Dekker RJ (1987). The weeds: description, ecology and control. Weeds of rice in Indonesia [edited by Soerjani, M. Tjitrosoepomo, G.] Jakarta, Indonesia, Balai Pustaka 24-565.

 

Lemmens RHMJ (2003). Crassocephalum crepidioides (Benth.) S. Moore. In: Lemmens RHMJ & Bunyapraphatsara N. (Editors). Plant Resources of South-East Asia No 12(3). Medicinal and poisonous plants 3. Backhuys Publishers, Leiden, Netherlands pp. 140-141.

 

Odukoya OA, Inya-Agha SA, Segun FA, Sofidiya MO, Ilori OO (2007). Antioxidant Activity of Selected Nigerian Green Leafy Vegetables. American Journal of Food Technology 2(3):169-175.
Crossref

 

Omotayo MA, Avungbeto O, Sokefun OO, Eleyowo OO (2015). Antibacterial activity of Crassocephalum crepidioides (fireweed) and Chromolaena odorata (siam weed) hot aqueous leaf extract. International Journal of Pharmacy and Biological Sciences (e-ISSN: 2230-7605) 5(2):114-122.

 

Otsuka H (2006). Purification by solvent extraction using partition coefficient. In: Sarker SD, Latif Z, Gray AI, editors. Natural Products Isolation. Methods in Biotechnology. Vol. 20. Humana Press Inc., Totowa, NJ. pp. 269-273.
Crossref

 

Owokotomo IA, Ekundayo O, Oladosu IA, Aboaba SA (2012). Analysis of the Essential Oils of Leaves and Stems of Crassocephalum crepidioides growing in South Western Nigeria. International Journal of Chemistry 4(2):34-37. 
Crossref

 

Oyelakin AS, Ayodele MS (2013). Morphotaxonomic evaluation of the relationship between four species of Crassocephalum (Moench.) S. Moore (Asteraceae) in southwestern Nigeria. Scientific Research and Essays 8(33):1629-1636.
Crossref

 

Rajesh KJ (2011). Terpene composition of Crassocephalum crepidioides from Western Ghats region of India. International Journal of Natural Products Research 1(2):19-22.

 

Randall RP (2012). A Global Compendium of Weeds. Perth, Australia. Department of Agriculture and Food Western Australia, 1124 p.

 

Sakpere AMA, Adedeji O, Folashade AT (2013). Flowering, Post-pollination Development and Propagation of Ebolo (Crassocephalum crepidioides (Benth.) S. Moore) in Ile-Ife, Nigeria. Journal of Science and Technology 33(2):37-49.
Crossref

 

Salisu TF, Okpuzor JE, Jaja SI (2019). Identification, characterization and quantification of chemical compounds in selected edible wild leafy vegetables. Ife Journal of Science 21(1):215-227. 
Crossref

 

Santos C, Salvadori MS, Mota VG, Costa LM, Cardoso de Almeida A, Lopes de Oliveira GA, Costa JP, de Sousa DP, Mendes de Freitas R, Nóbrega de Almeida R (2013). Antinociceptive and antioxidant activities of phytol in vivo and in vitro Models. Neuroscience Journal 949452:1-9. 
Crossref

 

Scanga SE, Hasanspahič B, Zvorničanin E, Samardžić Koženjić J, Rahme AK, Shinn-Thomas JH (2018). Erythritol, at insecticidal doses, has harmful effects on two common agricultural crop plants. PLoS ONE 13(4). 
Crossref

 

Smith FI, Eyzaguirre P (2007). Africa Leafy vegetables: Their Role in the World Health Organization Global Fruit and Vegetable initiative. Africa Journal of Food Agriculture and Nutrition 7(3).

 

Thakur S, Koundal R, Kumar D, Maurya AK, Padwad YS, Lal B, Agnihotri VK (2018). Volatile composition and cytotoxic activity of aerial parts of Crassocephalum crepidioides growing in Western Himalaya, india. Indian Journal of Pharmaceutical Sciences 81(1):167-172.
Crossref

 

Tomimori K, Nakama S, Kimura R, Tamaki K, Ishikawa C, Mori N (2012). Antitumor activity and macrophage nitric oxide producing action of medicinal herb, Crassocephalum crepidioides. BMC Complementary and Alternative Medicine 12(1):78.
Crossref

 

Vanderpas J (2003). Goitrogens and Antithyroid compounds; In Encyclopedia of Food Sciences and Nutrition (Second Edition).
Crossref

 

Wijaya S, Nee TK, Jin KT, Din WM, Wiart C (2011). Antioxidant, Anti- Inflammatory, Cytotoxicity and Cytoprotection Activities of Crassocephalum crepidioides (Benth.) S. Moore. Extracts and Its Phytochemical Composition. European Journal of Scientific Research 67(1):157-165.