African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 357

Table of Content: February 2008; 2(2)

February 2008

Development and validation of LC method for the determination of leflunomide in pharmaceutical formulations using an experimental design

A rapid and sensitive RP-HPLC method with UV detection (260 nm) for routine analysis of leflunomide in a pharmaceutical formulation was developed. Chromatography was performed with mobile phase containing a mixture of acetonitrile and phosphate buffer (60:40, v/v) with flow rate of 0.8 ml min−1. Quantitation was accomplished with internal standard method.  The procedure was validated for linearity...

Author(s): Srinivas Rao V, Sunanda K. K, Narasimha Rao M., Allam Appa Rao, Maheswari IL and Srinubabu G

February 2008

Enhancing trends of intensity signal of trace level Hf in zirconium oxide using AES sequential addition method

A sensitive, rapid and simple method to detect Hf at trace level in Zr has been described. It is based on the sequential addition of sample after each pre excitation period, in presence of graphite as buffer. The improvement with respect to the other published procedures lies in the use of solid powdered sample, omitting the step of wet chemistry or use of any optical filter. The enhancing trends of intensity curves...

Author(s): Ishrat Rehana and Saeed Ahmed