African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Antimicrobial activity of essential oil of Cordia globosa

Miguel Melissa
  • Miguel Melissa
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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García-Bores Ana
  • García-Bores Ana
  • Laboratorio de Fitoquímica, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Meraz Samuel
  • Meraz Samuel
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Piedra Elizabeth
  • Piedra Elizabeth
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Ávila Marisol
  • Ávila Marisol
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Serrano Rocío
  • Serrano Rocío
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Orozco Julieta
  • Orozco Julieta
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Jiménez-Estrada Manuel
  • Jiménez-Estrada Manuel
  • Instituto de Química, Universidad Nacional Autónoma de México. Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, D.F., México.
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Chavarría Juan Carlos
  • Chavarría Juan Carlos
  • Unidad Académica de Energía Renovable, Centro de Investigación Científica de Yucatán, A.C. C.P. 97200 Mérida, Yucatán, México.
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Peñalosa Ignacio
  • Peñalosa Ignacio
  • Laboratorio de Fitoquímica, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Ávila José Guillermo
  • Ávila José Guillermo
  • Laboratorio de Fitoquímica, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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Hernández Tzasna
  • Hernández Tzasna
  • Laboratorio de Farmacognosia, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Edo. de México, México.
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  •  Received: 01 September 2015
  •  Accepted: 19 November 2015
  •  Published: 22 March 2016

Abstract

Cordia globosa is used to treat gastrointestinal diseases in San Rafael Coxcatlan, Puebla, Mexico; however, its medicinal properties have not been investigated. This study reports the chemical composition and the antimicrobial effect of C. globosa essential oil. The essential oil of aerial parts was obtained by steam distillation and 25 compounds were identified by gas chromatography-mass spectrometry (GC-MS). The major constituent was α-pinene (38.4%). Antimicrobial activities were tested on 6 bacterial and 9 fungi strains. The most sensitive strain was Vibrio cholera (minimum inhibitory concentration [MIC], 0.060 mg/ml). These results show the chemical composition and biological properties of essential oil of C. globosa. The results validate the medicinal use of C. globosa.

Key words: Cordia globosa, Boraginaceae, antimicrobial activity, essential oil.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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