African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Antibacterial evaluation of selected Moroccan medicinal plants against Streptococcus pneumoniae

K. Warda1, M. Markouk1*, K. Bekkouche1, M. Larhsini1 A. Abbad1, A. Romane2 and M. Bouskraoui3
1Laboratory of Biotechnology, Protection and Valorisation of Plant Resources, Phytochemistry and Pharmacology of Aromatic and Medicinal Plant Unit, Faculty of Sciences, Semlalia, Marrakesh, Morocco. 2Laboratory of Applied Organic Chemistry, Faculty of Sciences, Semlalia, Marrakesh, Morocco. 3Laboratory of Microbiology and Virology, Faculty of Medicine and Pharmacy, Marrakesh, Morroco.
Email: [email protected]

  •  Accepted: 12 February 2009
  •  Published: 31 March 2009

Abstract

In Morocco, most people particularly in rural areas use medicinal plants to treat diseases. In order to find new anti-pneumococcal extracts, an ethnobotanical survey has been conducted in different regions of Marrakech (south of Morocco). Four plants often cited by traditional practitioners (Marrubium vulgare, Thymus pallidusEryngium ilicifolium and Lavandula stoechas) are tested againstStreptococcus pneumoniae responsible for pharyngitis, rhinitis, otitis and sinusitis infections. Aqueous and methanol extracts have been prepared and tested on S. pneumoniae collected in four regions of Marrakesh. A significant activity has been observed with methanol extracts of three of the plants; M. vulgare, T. pallidus andL. stoechas (MIC= 256 µg/ml).

 

 Key words: Streptococcus pneumoniae, antibacterial activity, medicinal plants, phytochemical screening