African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2288

Full Length Research Paper

Antioxidant and antibacterial activity of the extracts of Echinophora platyloba D.C

Reza Sharafati-chaleshtori1, Mahmoud Rafieian-kopaei2*, Seifollah Mortezaei2, Ali Sharafati-chaleshtori2 and Elham Amini2
1Department of Food Hygiene, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran. 2Medical Plants Research Center, Shahre-kord University of Medical Sciences, Shahre-kord, Iran.
Email: [email protected]

  •  Accepted: 03 September 2012
  •  Published: 31 October 2012

Abstract

Hydroalcholic and aqueous extracts of Echinophora platyloba D.C were screened for their possible antioxidant activity by β-carotene-linoleic acid and antibacterial effects using the microdilution method for Alcaligenes faecalisSerratia marcescensProvidencia rettgeri andListeria monocytogenes. Total phenols, flavonols and flavonoids were determined colorimetrically. In the β-carotene-linoleic acid system, oxidation was effectively inhibited by aqueous extract. The Minimum Inhibitory Concentration (MIC) for ethanolic and aqueous extracts was in between the range of 31.25 and 62.5 mg/ml. Minimum Bactericidal Concentrations (MBC) was between 31.25 and 250 mg/ml for ethanolic and aqueous extracts. Total phenols were 138±3.25 mg/g and 230±3.26 mg/g Gallic acid equivalent, total flavonols were 132±3.87 mg/g and 88±3.3 mg/g and flavonoids were 127±1.63 mg/g and 92±3.26 mg/g Rutin equivalent, respectively. These findings indicate that different plant extracts can be used in food protection conservation and alternative for synthetic preservatives.

 

Key words: Echinophora platyloba, antioxidant activity, antibacterial activity, extract.