Abstract

n the case of diabetes, hyperglycemia appears to be a significant contributor to oxidative stress which is also linked to diabetes related complications. In this study, we evaluated the effects of Ginkgo biloba L. and Camellia sinensis L. leaves extracts on oxidative damage in type 2 diabetic patients with surrounding diabetic complications. We found no significant effects of Green tea and Gingko biloba extracts on antioxidative enzymes (superoxide dismutase, catalase and glutathione peroxidase) and Total antioxidant status. However, G. biloba extract significantly reduced the amount of malondialdehyde and 4-hydroxy-2-nonenal (p < 0.05) while the Green tea extract and mix of both extracts did not have significant effects. Overall, the present findings are not beneficial in diabetic patients with more acute diabetic complications and further study in different circumstance needs to be done.

Key words: Gingko biloba extract, Camellia sinensis extract, antioxidant, oxidative stress.