African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2108

Review

Vascular endothelial growth factor (VEGF) in cancer

Hina Manzoor1, Muhammad Imran Qadir2*, Khizar Abbas1 and Muhammad Ali2
  1College of Pharmacy, GC University, Faisalabad, Pakistan. 2Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
Email: [email protected]

  •  Received: 03 October 2014
  •  Accepted: 03 October 2014
  •  Published: 08 October 2014

Abstract

Angiogenesis plays crucial part in the formation and progression of tumor, and vascular endothelial growth factor (VEGF) is one of the most important cytokine which aids in the growth of tumor cells. In various tumors whether locally invasive or metastasize to distal parts, elevated levels of VEGF is observed in blood through angiogenesis, this leads to progression of cancer.

 

Key words: Vascular endothelial growth factor (VEGF), cancer.