African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Retrospective analysis of medication for 508 cases of type II diabetes patients

Xiao-lan Zhou, Yuan-xi Gu and Jing-wen Gu*
Worldwide Medical Center, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Email: [email protected]

  •  Accepted: 07 September 2012
  •  Published: 22 January 2013

Abstract

The aim of this study was to investigate the medication status of 508 patients with type IIdiabetes admitted to Huashan Hospital, and to guide their clinical medication. The data of the 508 patients with type II diabetes who were admitted to Huashan Hospital between July, 2010 and December, 2010 were collected and analyzed. In 508 patients, acarbose was the most frequently prescribed medication (n = 337, 66.34%), the highest frequency of acarbose was 66.34% (n = 337). Metformin which belongs to the biguanide group accounted for 20.28%. Pioglitazone which belongs to thiazolidinedione group had the lowest frequency of use, and was only 1.38% (n = 7), and patients were often treated with combination therapy (n = 194, 38.18 %). A total of 431 patients (85%) had chronic diabetes complications (state which ones: macro or micro vascular complications). Among the diabetic patients, age groups in 40 to 80 had the highest probability of illness and the incidence rate increases with age; therefore, this group should take regular medical examinations to prevent diabetes induced complications. In the choice of medication, prescription drugs like acarbose and other α-glucosidase inhibitors, at the same time, combined medication with pancreatic kinionogenase are preferred. Enteric-coated tablets or other drugs to treat high blood pressure diabetes, heart disease, nervous system damage and other complications are also recommended.

 

Key words: Type II diabetes, combined medication, age related, complication, biguanide.