African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Analgesic activity of Ruta graveolens L. (Rue) extracts

Micael R. Cunha
  • Micael R. Cunha
  • Center for Biological Sciences and Health, Mackenzie Presbyterian University, São Paulo, São Paulo, Brazil.
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Tahira S. Melo
  • Tahira S. Melo
  • Center for Biological Sciences and Health, Mackenzie Presbyterian University, São Paulo, São Paulo, Brazil.
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Fatima M. M. Magri
Jan C. Delorenzi*
  • Jan C. Delorenzi*
  • Center for Biological Sciences and Health, Mackenzie Presbyterian University, São Paulo, São Paulo, Brazil.
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  •  Received: 07 August 2014
  •  Accepted: 22 December 2014
  •  Published: 08 January 2015

References

Effects of Some Jordanian Medicinal Plant Extracts. J. Ethnopharmacol. 60(2):117-124.
Crossref
 
Barbosa KA, Cruz EDN, Silva JA, Lourenço TMA, Santos NAA (2007). Técnica de condicionamento operante dentro do laboratório. In: Encontro de iniciação à docência, 10. João Pessoa, 2007, Anais. Universidade Federal do Paraíba: Centro de Ciências Humanas. Letras e Artes.
 
Brown VK, Robinson J, Stevenson DE (1963). A note on the toxicity and solvent properties of dimethyl sulphoxide. J. Pharm. Pharmacol. 15(1):688-692.
Crossref
 
Carvalho AC, Balbino EE, Maciel A, Perfeito JP (2008). Situação do registro de medicamentos fitoterápicos no Brasil. Rev. Bras. Farmacogn. João Pessoa 18:2.
 
Conway GA, Slocumb JC (1979). Plants used as abortifacients and emmenagogues by Spanish New Mexicans. J. Ethnopharmacol. 1(3):241-261.
Crossref
 
Desse J, Hulse SHA (1975). Psicologia da aprendizagem. 1ª ed. São Paulo: Livraria Pioneira Editora.
 
De Freitas, Tanise Gonçalves; Augusto, Patrice Martins; Montanari, Tatiana (2005). Effect of Ruta graveolens L. on pregnant mice. Contraception 71(1):74-77.
Crossref
 
Hale A, Meepagala KM, Oliva A, Aliotta G, Duke SO (2004). Phytotoxins from Leaves of Ruta graveolens. Agric. Food Chem, 52:3345-3349.
Crossref
 
Ivanova A, Mikhova B, Najdenski H, Tsvetkova I, Kostova I (2005). Antimicrobial and cytotoxic activity of Ruta graveolens. Fitoterapia 76:344-347.
Crossref
 
Jacob SW, Wood DC (1967). Dimethyl sulfoxide (DMSO) toxicology, pharmacology and clinical experience. Am. J. Surgery 114(3):414-426.
Crossref
 
Khouri NA, El-Akawi Z (2005). Anti-androgenic activity of Ruta graveolens L in male albino rats with emphasis on sexual and aggressive behavior. Neuroendocrinol. Lett. 26:823-829.
Pubmed
 
Kostova I, Ivanova A, Mikhova B, Klaiber I (1999). Alkaloids and coumarins from Ruta graveolens. Chem. Monthly 130(5):703-707.
Crossref
 
Meepagala KM, Schrader KK, Wedge DE, Duke SO (2005). Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs. Phytochemistry 66:2689-2695.
Crossref
 
Mendes ZF, Lima ER, Franco ES, Oliveira RA, Aleixo GA, Monteiro VL (2008). Avaliação da atividade antimicrobiana da tintura e pomada de Ruta graveolens (Arruda) sobre bactérias isoladas de feridas cutâneas em cães. Med. Vet. 2:32-36.
 
Nogueira FLP, Fernandes SBO, Reis GM, Matheus ME, Fernandes PD, Lage CLS, Menezes FS (2005). Atividade analgésica e antiedematogênica de Polygala paniculata L. (Polygalaceae) selvagem e obtida por micropropagação. Rev. Bras. Farmacogn. João Pessoa 15:4.
 
Preethi KC, Kuttan G, Kuttan R (2006). Anti-tumour activity of Ruta graveolens extract. Asian Pacific J. Cancer Prevent. 7(3):439.
Pubmed
 
Raghav SK, Gupta B, Agrawal C, Goswami K, Das H (2006). Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells. J. Ethnopharmacol. 104:234-239.
Crossref
 
Rodrigues E, Duarte-Almeida JM, Pires JM (2010). Perfil farmacológico e fitoquímico de plantas indicadas pelos caboclos do Parque Nacional do Jaú (AM) como potenciais analgésicas. Parte I. Rev. Brasileira de Farmacogn. 20:981-991.
Crossref
 
Roehsig M, Sant'anna ZSG, Salles KRRD, Dos Santos MF, Yonamine M (2011). Abortifacientes: efeitos tóxicos e riscos. Saúd. Ética Justiça 16:1-8.
 
San Miguel, Elia (2003). Rue (Ruta L., Rutaceae) in traditional Spain: frequency and distribution of its medicinal and symbolic applications. Econ. Botany 57(2):231-244.
Crossref
 
Sathesh BP, Divakar G, Jangid MK, Purohit KK (2010). Evaluation of analgesic activity of methanolic extract of Trapa natans l. var. Bispinosa roxb. Roots. J. Curr. Pharm. Res. 1:8-11.
 
Schultz V, Haensel R, Tyler VE (1998). Rational phytotherapy. A physician's guide to herbal medicine. Springer, Berlin. P 72.
Crossref
 
Sharma A, Bhatia S, Kharya MD, Gajbhiye V, Ganesh N, Namdeo AG, Mahadik KR (2011). Anti-inflammatory and analgesic activity of different fractions of Boswellia serrata. Int. J. Phytomed. 2:1.
 
Skinner BF (1974). Ciência e Comportamento Humano. 2ª ed. São Paulo: EDART.
 
Turan-Zitouni G, Sıvacı M, Kılıç FS, Erol K (2001). Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity. Eur. J. Med. Chem. 36(7):685-689.
Crossref
 
Wilson JE, Brown DE, Timmens EK (1965). A toxicologic study of dimethyl sulfoxide. Toxicol. Appl. Pharmacol. 7(1):104-112.
Crossref
 
Worthley EG, Schott C.D (1969). The toxicity of four concentrations of DMSO. Toxicol. Appl. Pharmacol. 15(2):275-281.
Crossref

 

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