References
Adeyemi OO, Akindele AJ, Yemitan OK, Aigbe FR, Fagbo FI (2010). Anticonvulsant, anxiolytic and sedative activities of the aqueous root extract of Securidaca longepedunculata Fresen. J. Ethnopharmacol. 130(2):191-195. |
|
Adeyemi OO, Yemitan OK, Taiwo AE (2006). Neurosedative and muscle-relaxant activities of ethyl acetate extract of Baphia nitida AFZEL. J. Ethnopharmacol. 106(3):312-316. |
|
Adeyemi OO, Okpo SO, Ogunti OO (2002). Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana Mill (Lauraceae). Fitoterapia, 73(5):375-380. |
|
Al-Naggar TB, Gomez-Serranillos MP, Carretero ME, Villar AM (2003). Neuropharmacological activity of Nigella sativa L. extracts. J. Ethnopharmacol. 88(1):63-68. |
|
Olatokunboh AO, Kayode YO, Adeola OK (2009). Anticonvulsant activity of Rauvolfia vomitoria (Afzel). Afr. J. Pharm Pharmacol. 3(6):319-322. |
|
Antia BS, Okokon JE, Okon PA (2005). Hypoglycemic activity of aqueous leaf extract of Persea americana Mill. Indian J. Pharmacol. 37(5):325. |
|
Arukwe U, Amadi BA, Duru MKC, Agomuo EN, Adindu EA, Odika PC, Anudike J(2012). Chemical composition of Persea americana leaf, fruit and seed. IJRRAS.11(2):346-349. |
|
Asaolu MF, Asaolu SS, Fakunle JB, Emman-Okon BO, Ajayi EO, Togun RA (2010). Evaluation of in-vitro antioxidant activities of methanol extracts of Persea americana and Cnidosculus aconitifolius. Pak. J. Nutr. 9(11):1074-1077. |
|
Balunas MJ, Kinghorn AD (2005). Drug discovery from medicinal plants. Life Sci. 78(5):431-441. |
|
Bhattacharya PK, Bhattacharya L, Jain RK, Agarwal RC (2003). Post anaesthesia shivering (PAS): A review. Indian J. Anaesth. 47(2):88-93. |
|
Castel-Branco MM, Alves GL, Figueiredo IV, Falcão A, Caramona MM (2009). The maximal electroshock seizure (MES) model in the preclinical assessment of potential new antiepileptic drugs. Methods Find. Exp. Clin. Pharmacol. 31(2):101-106. |
|
Chen H, Morrell PL, Ashworth VE, de la Cruz M, Clegg MT (2009). Tracing the geographic origins of major avocado cultivars. J. Heredity 100(1):56-65. |
|
de Carvalho RSM, Duarte FS, de Lima TCM (2011). Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice. Behav. Brain Res. 221(1):75-82. |
|
De Sarro A, Cecchetti V, Fravolini V, Naccari F, Tabarrini O, De Sarro G (1999). Effects of novel 6-desfluoroquinolones and classic quinolones on pentylenetetrazole-induced seizures in mice. Antimicrob. Agents Chemother. 43(7):1729-1736. |
|
Sousa DPD, Nóbrega FF, de Morais LC, Almeida RND (2009). Evaluation of the anticonvulsant activity of terpinen-4-ol. Z. Naturforsch. C. 64(1-2):1-5. |
|
Dzeufiet PD, Mogueo A, Bilanda DC, Aboubakar BF, Tédong L, Dimo T, Kamtchouing P (2014). Antihypertensive potential of the aqueous extract which combine leaf of Persea americana Mill. (Lauraceae), stems and leaf of Cymbopogon citratus (D.C) Stapf. (Poaceae), fruits of Citrus medical L. (Rutaceae) as well as honey in ethanol and sucrose experimental model. BMC Complement. Altern. Med. 14:507. |
|
Edem D1, Ekanem I, Ebong P (2009). Effect of aqueous extracts of alligator pear seed (Persea americana Mill.) on blood glucose and histopathology of pancreas in alloxan-induced diabetic rats. Pak. J. Pharm. Sci. 22(3):272-6. |
|
Ezuruike UF, Prieto JM (2014). The use of plants in the traditional management of diabetes in Nigeria:Pharmacological and toxicological considerations. J. Ethnopharmacol. 155(2):857-924. |
|
Fabricant DS, Farnsworth NR (2001). The value of plants used in traditional medicine for drug discovery. Environ. Health Perspect. 1:69-75. |
|
Gavhane YN, Yadav AV (2012). Loss of orally administered drugs in GI tract. Saudi Pharm. J. 20(4):331-44 |
|
Gonzalez-Trujano ME, Carrera D, Ventura-Martinez R, Cedillo-Portugal E, Navarrete A (2006). Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice. J. Ethnopharmacol. 106(1):129-135. |
|
Guo L, Wang S, Zhang J, Yang G, Zhao M, Ma W, Huang L (2013). Effects of ecological factors on secondary metabolites and inorganic elements of Scutellaria baicalensis and analysis of geoherblism. Sci. China Life Sci. 56(11):1047-1056. |
|
Hegde K, Thakker SP, Joshi AB, Shastry CS, Chandrashekhar KS (2009). Anticonvulsant activity of Carissa carandas Linn. root extract in experimental mice. Trop. J. Pharm. Res. 8:(2). |
|
Helliön-Ibarrola MC, Ibarrola DA, Montalbetti Y, Villalba D, Heinichen O, Ferro EA (1999). Acute toxicity and general pharmacological effect on central nervous system of the crude rhizome extract of Kyllinga brevifolia Rottb. J. Ethnopharmacol. 66(3):271-276. |
|
Herrera-Ruiz M, Gutiérrez C, Jiménez-Ferrer JE, Tortoriello J, Mirón G, León I (2007). Central nervous system depressant activity of an ethyl acetate extract from Ipomoea stans roots. J. Ethnopharmacol. 112(2):243-247. |
|
Imafidon KE, Amaechina FC (2010). Effects of aqueous seed extract of Persea americana Mill.(avocado) on blood pressure and lipid profile in hypertensive rats. Adv. Biol. Res. 4(2):116-121. |
|
Jiménez-Arellanes A, Luna-Herrera J, Ruiz-Nicolás R, Cornejo-Garrido J, Tapia A, Yépez-Mulia L (2013). Antiprotozoal and antimycobacterial activities of Persea americana seeds. BMC Complement. Altern. Med. 13:109. |
|
Deraedt R, Jouquey S, Delevallée F, Flahaut M (1980). Release of prostaglandins E and F in an algogenic reaction and its inhibition. Eur. J Pharmacol. 11:61(1):17-24. |
|
Hegde K, Thakker SP, Joshi AB, Shastry CS, Chandrashekhar KS (2009). Anticonvulsant activity of Carissa carandas Linn. root extract in experimental mice. Trop. J. Pharma. Res. 8(2). |
|
Koffi N, Kouakou EA, Dodiomon S (2009). Effect of aqueous extract of Persea americana seeds on the glycemia of diabetic rabbits. Eur. J. Sci. Res. 26(3):76-385. |
|
Leite JJG, Brito ÉHS, Cordeiro RA, Brilhante RSN, Sidrim JJC, Bertini L M, Rocha MFG (2009). Chemical composition, toxicity and larvicidal and antifungal activities of Persea americana (avocado) seed extracts. Rev. Soc. Bras. Med. Trop. 42(2):110-113. |
|
Lorke D (1983). A new approach to practical acute toxicity testing. Arch. Toxicol. 54(4):275-287. |
|
Löscher W, Schmidt D (1988). Which animal model should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2(3):145-81. |
|
Macdonald RL, Kelly KM (1995). Antiepileptic drug mechanisms of action. Epilepsia. 36(2):S2-12. |
|
Matsusaka Y, Kawabata J, Kasai T (2003). Antioxidative constituents in avocado (Persea americana Mill.) seeds. J. Jpn. Soc. Food Sci. Technol. 50(11):550-552. |
|
Mimura M, Namiki A, Kishi R, Ikeda T, Miyake H (1990). Antagonistic effect of physostigmine on ketamine-induced anaesthesia. Psychopharmacology (Berl). 102(3):399-403. |
|
Mir AM, Sawhney SS, Jassal MMS (2013). Qualitative and quantitative analysis of phytochemicals of Taraxacum officinale. Wudpecker J. Pharm. Pharmacol. 2(1):001-005. |
|
Nagashima K (2006). Central Mechanisms for Thermoregulation in a Hot Environment. Ind. Health 44(3):359-67. |
|
Nayak BS, Raju SS, Chalapathi Rao AV. (2008). Wound healing activity of Persea americana (avocado) fruit: A preclinical study on rats. J. Wound Care 17(3):123-6. |
|
Nevins ME, Arnolde, SM (1989). A comparison of the anticonvulsant effects of competitive and non-competitive antagonist of the N-methyl-d-aspartate receptor. Brain Res. 503(1):1-4 |
|
Newman DJ, Cragg GM (2012). Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Natural Prod. 75(3)311-335. |
|
Nwaogu LA, Alisi CS, Ojiako OA (2009). Studies on the nutritional and phytochemical properties of Persea americana seed. Bio-Res. 6(1):320-322. |
|
Odo CE, Nwodo OF, Joshua PE, Ugwu OP, Okonkwo CC (2013). Acute toxicity investigation and anti-diarrhoeal effect of the chloroform–methanol extract of the seeds of Persea americana in albino rats. Iran J. Pharm. Res. 13(2):651-658. |
|
Ojewole JA, Amabeoku, GJ (2006). Anticonvulsant effect of Persea americana Mill (Lauraceae) (Avocado) leaf aqueous extract in mice. Phytother Res. 20(8):696-700. |
|
Okonta M, Okonta L, Aguwa CN (2007). Blood glucose lowering activities of seeds of Persea americana on alloxan induced diabetic rats. Nigerian J. Nat. Prod. Med. 11:26-28. |
Onigbogi O, Ajayi AA, Ukponmwan OE (2000). Mechanisms of chloroquine-induced body scratching behaviour in rats; Evidence of involvement of endogenous opioid peptides. Pharmacol. Biochem. Behav. 65(2):333-337. |
|
Owolabi MA, Jaja SI, Coker HA (2005). Vasorelaxant action of aqueous extract of the leaves of Persea americana on isolated thoracic rat aorta. Fitoterapia. 76(6):567-573. |
|
Oyemitan IA, Iwalewa EO, Akanmu MA, Olugbade TA (2008). Sedative, Hypothermic and Muscle Relaxant Effects of the Essential Oil of Dennettia tripetala G. Baker (Annonaceae) in Mice. Ife J. Sci. 10(1):1-9. |
|
Padilla-Camberos E, Martínez-Velázquez M, Flores-Fernández JM, Villanueva-Rodríguez S (2013). Acute toxicity and genotoxic activity of avocado seed extract (Persea americana Mill cv Hass). Available at: http://dx.doi.org/10.1155/2013/245828. |
|
Park JH, Cha HY, Seo JJ, Hong JT, Han K, Oh KW (2005). Anxiolytic-like effects of ginseng in the elevated plus-maze model: comparison of red ginseng and sun ginseng. Progress in Neuro-Psychopharmacol. Biol. Psiquiatr. 29(6):895-900. |
|
Pellow S, Chopin P, File SE, Briley M (1985). Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. Neurosci. Methods 14(3):149-167. |
|
Pond SM, Tozer TN (1984). First-pass elimination. Basic concepts and clinical consequences. Clin. Pharmacokinet. 9(1):1-25. |
|
Pourgholami MH, Kamalinejad M, Javadi M, Majzoob S, Sayyah M (1999). Evaluation of the anticonvulsant activity of the essential oil of Eugenia caryophyllata in male mice. J. Ethnopharmacol. 64(2):167-171. |
|
Ramanjaneyulu R, Ticku MK (1984). Interactions of pentylenetetrazol and tetrazole analogues with the picrotoxin site of the benzodiazepine-GABA receptor ionophore complex. Eur. J. Pharmacol. 98: 337-345. |
|
Rang HP, Dale MM, Ritter JM, Moore PK (2007). Pharmacology, 6th ed. Churchill Livingstone. Edinburgh. pp. 557-587. |
|
Rodríguez- Carpena JG, Morcuende D, Andrade MJ et al. (2011). Avocado (Persea americana Mill.) Phenolics, in vitro antioxidant and antimicrobial activities, and inhibition of lipid and protein oxidation in porcine patties. J. Agric. Food Chem. 59(10):5625-5635. |
|
Rowlands DB, Stallard TJ, Watson RDS et al. (1980). The influence of physical activity on arterial pressure during ambulatory recordings in man. Clin. Sci. 58:116-117. |
|
Shenoy AK, Miyahara JT, Swinyard EA, Kupferberg HJ (1982). Comparative anticonvulsant activity and neurotoxicity of clobazam, diazepam, phenobarbital, and valproate in mice and rats. Epilepsia 23(4):399-408. |
|
Silva J, Abebe W, Sousa SM, Duarte VG, Machado MIL, Matos FJA (2003). Analgesic and anti-inflammatory effects of essential oil of Eucalyptus. J. Ethnopharmacol. 89(2):277-283. |
|
Sivam SP, Nabeshima T, Ho IK (2004). Acute and chronic effects of pentobarbital in relation to postsynaptic GABA receptors: A study with muscimol. J. Neurosci. Res. 7(1):37-47. |
|
Söderpalm B, Hjorth S, Engel JA (1989). Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test. Pharmacol. Biochem. Behav. 32(1):259-265. |
|
Sousa DPD, Nóbrega FF, de Morais LC, Almeida RND (2009). Evaluation of the anticonvulsant activity of terpinen-4-ol. Z. Naturforsch. C. 64(1-2):1-5. |
|
Swinyard EA, Woodhead JH, White HS, Franklin MR (1989). Experimental selection, quantification and evaluation of anticonvulsants. In: Levy R, Mattson R, Meldrum BS, Penry JK, Dreifuss FE. (Eds), Antiepileptic Drugs, 3rd ed., Raven Press New York. pp 85-102. |
|
Takeda H, Tsuji M, Matsumiya T (1998). Changes in head-dipping behaviour in the hole-board test reflect the anxiogenic and/or anxiolytic state in mice. Euro. J. Pharmacol. 350(1):21-29. |
|
Takenaga F, Matsuyama K, Abe S, Torii Y, Itoh S (2008). Lipid and fatty acid composition of mesocarp and seed of avocado fruits harvested at northern range in Japan. J. Oleo. Sci. 57(11):591-597. |
|
Ukwe CV, Nwafor SV (2005). Anti-ulcer activity of aqueous leaf extract of Persea americana (family-Lauraceae). Nig. J. Pharm. Res. 3(1):91-95. |
|
Vale TG, Matos FJA, De Lima TCM, Viana GSB (1999). Behavioural effect of essential oils from Lippia alba (Mill) N.E. Brown Chemotypes. J. Ethnopharmacol. 167(2):127-133. |
|
Viana GS, Bandeira MA, Matos FJ. (2003). Analgesic and anti-inflammatory effects of chalcones isolated from Myracrodruon urundeuva Allem. Phytomed. 10(2-3):189-95. |
|
Wang W, Bostic TR, Gu L (2010). Antioxidant capacities, procyanidins and pigments in avocados of different strains and cultivars. Food Chem. 122(4):1193-1198. |
|
Yadav AV, Kawale LA, Nade VS (2008).Effect of Morus alba L. (mulberry) leaves on anxiety in mice. Indian J. Pharmacol. 40(1):32-6. |
|
Zapata-Sudo G, Mendes TC, Kartnaller MA, Fortes TO, Freitas NF, Kaplan MA, Sudo RT (2010). Sedative and anticonvulsant activities of methanol extract of Dorstenia arifolia in mice. J. Ethnopharmacol. 130(1):9-12. |
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