March 2014
Protective effect of 2,2,2-trichloroethanol on peptidoglycan-induced inflammation in murine macrophages
The aim of this study was to investigate the effect of 2,2,2-trichloroethanol on peptidoglycan-induced murine macrophages inflammation. The effect of 2,2,2-trichloroethanol on the production of TNF-α and IL-6 by murine peritoneal macrophages with peptidoglycan-stimulation were investigated. Also, RAW264.7 macrophages transfected with a NF-κB luciferase reporter plasmid with the stimulation of peptidoglycan...
March 2014
Regulation of cartilage and inflammatory biomarkers in rheumatoid arthritis patients treated with green tea therapy
Most of the conventional rheumatoid arthritis (RA) drugs used have severe adverse reactions. Therefore, natural plant products are continuously being sought for the management of RA. In the present study, in vitro antioxidant, joint protective and anti-inflammatory activity of aqueous green tea extract (AGTE) was evaluated in 50 patients with early RA, 30 patients with established RA and 50 healthy control subjects. All...
March 2014
Effect of Korean arbor vitae (Thuja koraiensis) extract on antimicrobial and antiviral activity
The present study was carried out to develop a new natural product reagent which has antimicrobial and antiviral effect, so we assayed the extract from Korean Arbor vitae (Thuja koraiensis) on antimicrobial and antiviral in vitro. The antimicrobial activity was assayed at two gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis); two gram-negative bacteria (Escherichia coli, Salmonella typhimurium) and the...
March 2014
Awareness of epilepsy in pharmacy students in different universities of Karachi, Pakistan
The aim of this study was to determine knowledge and awareness regarding epilepsy among under graduate pharmacy students in Karachi, Pakistan. The questionnaire was distributed to the pharmacy students of 4th and 5th year in three different universities of Karachi, Pakistan from August to September, 2013 and the data was assessed using descriptive analysis. Five hundred questionnaires were distributed among the students...
March 2014
Antiviral, antimicrobial and anti-inflammatory activities of Urera baccifera (L.) Gaudich
Urera baccifera (Urticaceae) is a shrub used in folk medicine for rheumatic diseases and mycosis. This study aimed to test the antiviral, antinociceptive, anti-inflammatory and antimicrobial activities of U. baccifera leaves and roots. The cytotoxic and antiviral activity was evaluated against Herpes virus type 1, in vitro. The antimicrobial activity was determined by the broth microdilution method based on Clinical and...
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