African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2205

Table of Content: 15 November, 2016; 10(42)

November 2016

Use of zebrafish (Danio rerio) in experimental models for biological assay with natural products

Research on natural products is facing significant difficulty. The analysis "high-throughput screening" has limited effectiveness in their evaluation. This report on in vitro screening of pharmacological activity of the drugs candidate molecule by evaluating a single target. The presence of many substances in a natural extract makes this process unprecise. The zebrafish (Danio rerio, ZF) is well suited to...

Author(s): Igor Victor Ferreira dos Santos, Jonatas Lobato Duarte, Caio Pinho Fernandes, Hady Keita, Jesus Rafael Rodríguez Amado, Josué Arturo Velázquez-Moyado, Andrés Navarrete and José Carlos Tavares Carvalho,

November 2016

Antinociceptive and antioxidant activity of Calliandra umbellifera Benth

The genus, Calliandra is popularly used for renal pain, cystitis, prostate inflammation, fever and toothache. This study aimed at investigating the antinociceptive activity of methanolic crude extract (MCE) of Calliandra umbellifera, regarding chemical (acetic acid, formalin and glutamate tests) of nociception (in vivo) and the methanolic extract and hidrobutanolic phase (HBF) antioxidant activity by the...

Author(s): Tainá Souza Silva, Juliana de Medeiros Gomes, Diogo Vilar da Fonsêca, Camila Holanda de Albuquerque, Maria de Fátima Agra, Marcelo Sobral da Silva, Reinaldo Nóbrega de Almeida and Josean Fechine Tavares

November 2016

Effect of hydroethanolic extract from Calophyllum brasiliense Cambess on streptozotocin induced diabetic rats

Calophyllum brasiliense (Cb) belongs to the Clusiaceae family and it is generally used for diabetes treatment. The aim of this study was to evaluate the anti-diabetic effect of Cb’s hydroethanolic extract (CBE) on diabetic induced rats by streptozotocin and evaluate the content of polyphenols and tannins of the extract. The polyphenols and tannins evaluation in the extract were determinated by a...

Author(s): Helison de Oliveira Carvalho, Grace Suzan Lopes Lacerda, Adriana Maciel Ferreira, Larissa Daniele Machado Góes, Beatriz Martins de Sá, Mona Saout, Didier Bereau, Jean-charles Robinson, Rafael Lima Resque, Caio Pinho Fernandes and José Carlos Tavares Carvalho,