October 2017

Hepatoprotective effects of methanol extract of Alchornea cordifolia leaves against anti-tubercular drugs induced hepatotoxicity in rats

Alchornea cordifolia has been shown to be hepatoprotective against hepatotoxicity induced by high dose paracetamol in a model animal. However, its hepatoprotective effects against the hepatotoxicity induced by anti-tubercular drugs have not yet been studied, whereas anti-tubercular drugs are known to be hepatotoxic at therapeutic dose. The aim of this work was to evaluate the hepatoprotective effect of a methanol...

Author(s): Effo Kouakou Etienne, Kouakou Sylvain Landry, Irie-N’Guessan Amenan Geneviève, Akoubet Aminata and Kouakou-Siransy N’Doua Gisèle

October 2017

The effect of vanadium on rat hypercholesterolemia in the presence and absence of statins

Vanadium may or may not be a cholesterol-lowering agent. It could potentially be used as an additional therapy or alone in therapies for treatment of dyslipidemia. This study aimed to investigate the effect of vanadium on hypercholesterolemia in the presence and absence of statins. Sixty rats were divided into five groups. The first group was kept on a normal diet and the second group was kept on a high fat diet. The...

Author(s): Nasr L. R., Saber M. E., Hussam B., Salma A. R. and Muzaffar I.