September 2016

Involvement of pro-inflammatory cytokines and nociceptive pathways on the pharmacological activity of hydantoin derivative 5-(4-isopropylphenyl)-3-phenyl-imidazolidine-2,4-dione

Hydantoins are often reported as potent anticonvulsant drugs; however, recent studies have highlighted their antinociceptive potential. Based on these reports, this study investigated the antinociceptive and anti-inflammatory activities of the hydantoin derivative 5-(4-isopropylphenyl)-3-phenyl-imidazolidine-2,4-dione (IM-7) using animal models. Treated mice submitted to the acetic acid-induced writhing test showed...

Author(s): Fabíola Lélis de Carvalho, Diogo Vilar da Fonsêca, Antônia Rosangela Soares Penha, Mirian Graciela da Silva Stiebbe Salvadori, Paula Regina Rodrigues Salgado, Charlane Kelly Souto Pereira, Fagner Carvalho Leite, Márcia Regina Piuvezam, Severino Araújo de Sousa, Petrônio Filgueiras de Athayde-Filho, Liana Clébia de Morais Pordeus and Reinaldo Nóbrega de Almeida

September 2016

Activity of red wine polyphenols on endothelial no-synthase (eNOS)

Polyphenols (PPH) represent a group of chemical substances found in plants, characterized by the presence of more than one phenol unit. The largest and best studied polyphenols are the flavonoids. Polyphenols contained in red wine have beneficial effects on cardiovascular health. The aim of our research was a comparative and interactive study of four red wine polyphenols - resveratrol (R), quercetin (Q), kaempferol (K)...

Author(s): Naguibou Djibril, Eugene Selidji Attakpa, Habib Ganfon, Victor Bruno Omoregbe

September 2016

In vitro acaricidal activity of crude extracts of Schinus molle (L.) leaves against field population of Bophilus decoloratus and Rhipicephalus pulchellus ticks

Plant products are a rich source of bioactive organic chemicals and offer an advantage over synthetic pesticides as these are less toxic, less prone to development of resistance and easily biodegradable. The present study aimed at screening the acaricidal potential of crude methanolic and aqueous extracts of Schinus molle (L.) leaves on the adult Bophilus decoloratus and Rhipicephalus pulchellus cattle ticks, using in...

Author(s): Teka Feyera and Edilu Abdisa

September 2016

Analysis on effects of diets on antiretroviral therapy (ART) immune response among HIV/AIDS Patients in Eastern Ethiopia: Particular emphasis to camel dairy consumption

Diets and nutrition have critical effect on immune status of human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) patients and on recovery of immune competence after antiretroviral therapy (ART). A pilot study was conducted to explore associations between the dietary pattern of HIV/AIDS patients and their immune (CD4+ cell recovery) response following ART. A recall interview survey...

Author(s): Befikadu Urga Wakayo, Fentabil Getnet and Teka Feyera