December 2012
Aminonaphthoquinones as potential anti-breast cancer agents
A small library of compounds, including aminonaphthoquinones, heterocyclic and aromatic compounds, was synthesized to determine their antiproliferative activity against three mammalian cancer cell lines viz:cervical carcinoma (HeLa), breast adenocarcinoma (MCF-7) and T-cell leukaemia (Jurkat). Investigations into the effect of the compounds on coagulation and platelet activity were also undertaken. In particular, the...
December 2012
Free radical scavenging activity of Chinese traditional four substances decoction (FSD) extracts
This article examined the interactive effect among herbs extracts in combined use, compared with the effect of individual herbal extracts on 1,1-diphenyl picryl hydrazyl (DPPH). The Chinese traditional prescription, four substances decoction (FSD) consisted of 25 g ofAngelica sinensis (Umbelliferae, AS), 6 g of Ligusticum chuanxiong Hort. (Umbelliferae, LCH), 10 g of Paeonia...
December 2012
Antioxidant and a-glucosidase inhibitory activity of red raspberry (Harrywaters) fruits in vitro
[2,2-azino-bis(3-ethylbenzothiazoline)-6-sulphonic acid] Diammonium salt (ABTS) radical scavenging and ferric reducing antioxidant power (FRAP) assay were used to analyze the antioxidant activity of red raspberry (Harrywaters, HW) fruits with 2,6-Di-tert-butyl-4-methylphrnol (BHT) as positive controls and α-glucosidase inhibitory activity of HW extracts with acarbose as positive control in vitro. HW fruits...
December 2012
Effect of hyaluronic acid and vitamin E vaginal tablets on atrophic vaginitis: A randomized controlled trial
The aim of this study was to compare the effectiveness of the vaginal tablet of hyaluronic acid and vitamin E in the treatment of atrophic vaginitis. This randomized, double-blind comparisonstudy was carried out on 40 postmenopausal women with symptoms of vaginal atrophy at number one health educational center of Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran from August to December...
December 2012
Phytochemical, antioxidant and cytotoxic activities of Periploca aphyla and Mentha longifolia, selected medicinal plants of District Bannu, Pakistan
Mentha longifolia and Periphloca aphyla are a well known species widely applied in medicine as a constituent of various drugs, and are very liked in aromatherapy. The current study was desighned to investigate the phytochemical screening, cytotoxic and antioxidant capacity of methanolic extract of Mentha longifolia and Periphloca aphyla. The methanolic extract...
December 2012
Proteomic analysis of oxymatrine-induced changes in lung fibroblasts
Oxymatrine, one kind of alkaloids extracted from Sophora flavescens Ait, has been demonstrated to attenuate bleomycin-induced lung fibrosis. The mechanisms of this action are poorly known. This study aimed to use proteomics to provide new insights into the mechanisms of the pharmacological effects. Proteins from murine lung fibroblasts exposed to oxymatrine were separated by two-dimensional electrophoresis....
December 2012
Effects of different manufacturing methods on pharmaceutical properties and release kinetic models of ketoprofen sustained-release microparticles
Extrusion-spheronization and the fluid bed method are valuable commonly applied methods in microparticle production. However, the characteristics of resultants prepared by these two methods have seldom been compared. The aim of this study was to investigate differences in pharmaceutical properties and release kinetics of sustained-release ketoprofen microparticles prepared by different manufacturing processes....
December 2012
The level of awareness and use of anticoccidials in poultry farms in South Western Nigeria
This study investigated the level of awareness and usage of anticoccidial drugs and vaccines by poultry farms in southwestern geopolitical zones of Nigeria, using Lagos, Oyo, and Ogun states. A researcher-made questionnaire was administered to the selected poultry farms, poultry attendants and veterinarians. With the deduction of an attrition value of 10% on questionnaire retrieval, data from 72 respondents out of 80...
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