African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 8 December, 2013; 7(45)

December 2013

The clinical study of YiShenTongMai decoction in unstable angina complicated with glucose metabolism disorder

This study aimed to evaluate the clinical effects of YiShenTongMai decoction working with conventional Western drugs in patients with unstable angina complicated with glucose metabolism disorder. Seventy-six patients with unstable angina complicated with glucose metabolism disorder were randomly divided into two groups: 37 cases were allotted to the control group and were treated with conventional Western medicine; 39...

Author(s): Jianfang Ye, Pengwei Jia , Yamei Li and Guisheng Wang

December 2013

Pharmacological evaluation of Ziziphus nummularia leaves for phytotoxic and molluscicidal bioassays

Medicinal plants have curative properties due to the presence of various complex chemical substances of different composition which contain secondary metabolites. In the present study, the phytochemical screening of Ziziphus nummularia leaves were carried out to investigate their phytoconstituents like alkaloids, carbohydrates, protein, saponin, tannins, fixed oil, fats, volatile oil, glycosides, phenol and flavonoids....

Author(s): Sumaira Shah, Sirj ud Din Rehmanullah and Qaiser Jamal

December 2013

Antihyperglycemic effect and phytochemical screening of aqueous extract of Passiflora foetida (Linn.) on normal Wistar rat model

Passiflora foetida L. belonging to family Passifloraceae is used in Sri Lanka as a traditional medicine in the treatment of diabetes mellitus. This study was designed to examine the antihyperglycemic activity of the aqueous leaf extract of P. foetida in normoglycemic Wistar rats. The extract at a dose of 433 mg/kg (calculated on the basis of the traditional raw salad intake per meal) had a effect not significantly...

Author(s): M. A. Siriwardhene, A. M. Abeysekera, U. G. Chandrika and A. K. E. Goonetilleke

December 2013

Cassia abbreviata Oliv. A review of its ethnomedicinal uses, toxicology, phytochemistry, possible propagation techniques and Pharmacology

A variety of ethnotherapeutic properties and pharmacological actions has been attributed to Cassia abbreviata Oliv. which belong to the family Caesalpiniaceae. Reports from the literature have indicated the presence of a variety of compounds including alkaloids. Studies by various groups of investigators revealed that C. abbreviata possess antidiabetic, antioxidant and antimicrobial activity, thus lending...

Author(s): Mongalo N. I. and Mafoko B. J.

December 2013

Anti-anaemic effect of methanol seed extract of Sphenostylis stenocarpa (African yam bean) in Wistar albino rats

The African yam bean, Sphenostylis stenocarpa (Hoschst ex. A. Rich) Harms, Fabaceae, is one of the edible legumes cultivated in Africa for human and animal nutrition. The acute toxicity (LD50) test and haematological parameters of anaemic rats treated with the methanol extract of the plant seeds were investigated for days 0, 4 and 8. The extract was found not to be toxic up to 5000 mg/kg, indicating the safety of the...

Author(s): Okonkwo C. Christopher, Njoku U. Obioma and Mbah A. Mary

December 2013

Linezolid for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) nosocomial pneumonia: Queries continue

The latest published Linezolid in the treatment of subjects with nosocomial pneumonia proven to be due to methicillin-resistant Staphylococcus aureus (ZEPhyR) trial was a phase IV, randomized, double-blind, multicenter, comparator-controlled study comparing the efficacy of fixed-dose linezolid to dose-optimized vancomycin in hospitalized adults for the treatment of methicillin-resistant S. aureus (MRSA) nosocomial...

Author(s): Jian-Guo Tang, Chun-Hui Yang and Dan Xu