July 2017

“Environmental ritalinization”: Brain structural changes after exposition to methylphenidate residues

Methylphenidate, marketed as Ritalin, is an emerged pollutant found in wastewater. Methylphenidate exposure at pharmacological doses can modify brain metabolism, however, the consequences of environmental residues remains to be elucidated. This work presents the results of a chronic exposure to methylphenidate residual levels (0.1875 and 1.875 µg/L) consistent with the amount found in the environment. Animals were...

Author(s): Bruna Maraschin, Celestin Kabasele, Charise Dallazem Bertol, Maiara Cristina Soares Paixão, Natália Freddo, Marcelo Dutra Arbo and Luciana Grazziotin Rossato-Grando,