May 2019

Effect of Parkia biglobosa extract on open skin wound healing in dexamethasone- induced hyperglycaemia and histological assessment in rats

Glucocorticoid-induced diabetes mellitus (GIDM) is an abnormal increase in blood glucose associated with the use of glucocorticoids in a patient with or without a prior history of diabetes mellitus. This is a common and potentially harmful problem in clinical practice, affecting almost all medical specialties, but is often diffi¬cult to detect in clinical settings.  The objective of this study was to determine...

Author(s): Modupe Iretiola Builders, Oyepata Simeon Joseph and Akpobome Raymond Vhriterhire  

May 2019

Neferine and isoliensinine from Nelumbo nucifera induced reactive oxygen species (ROS)-mediated apoptosis in colorectal cancer HCT-15 cells

Several scientific reports documented the potent anti-cancer effect of various natural products  such as curcumin, epigallocatechin gallate (EGCG), resveretrol via the rise in reactive oxygen species (ROS) and dysfunction of anti-apoptotic gene expressions. The present study evaluated the anticancer potential of lotus derived alkaloids, neferine and isoliensinine on colorectal cancer HCT-15 (CRCs) cells....

Author(s): Prasath Manogaran, Narasimha Murthy Beeraka, Chih-Yang Huang, Viswanadha Vijaya Padma,