African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2205

Table of Content: 8 September, 2016; 10(33)

September 2016

Synthesis of 2-(benzylthio)benzimidazole, 2-[(benzimidazol-2-yl)methylthio]benzimidazole and structural analogues against Haemoncus contortus

The coupling of the derivatives of the 2-mercaptobenzimidazole 1 with the derivatives of the (chloromethyl)benzene 2 gives 2-(benzylthio)benzimidazole 4a-k on the one hand, and with the 2-(chlorométhyl)benzimidazole 3 on the other the 2-(benzimidazolyl methylthio) benzimidazole and analogues 5a-k. We determined the structures of all synthesized compounds by Nuclear Magnetic Resonance (NMR) and Mass Spectrometry...

Author(s): Sagne Jacques Akpa, Martial Venance Say, Roger Simplice Pépin Zoakouma, Bamba Fanté, Drissa Sissouma and Ané Adjou

September 2016

The effectiveness of dear healthcare professional letters as a risk minimization tool in Ghana

Dear Healthcare Professional (DHP) letter is a risk minimization tool used to inform health workers about new and emerging safety information during the marketing period of medicinal products. DHP letters in some cases may not be effective because targeted audience may not be aware of these letters or even understand them. The objectives of this study were to assess the effectiveness and relevance of DHP letters as...

Author(s): George Tsey Sabblah, Delese Mimi Darko, Abena Asamoa-Amoakohene and Adela Ashie

September 2016

Acute toxicity and hypoglycaemic activity of the leaf extracts of Persea americana Mill. (Lauraceae) in Wistar rats

Persea americana Mill. or avocado plant tree is well-known to people from the sub-Saharan part of Africa. Studies carried out earlier reported on the use of leaf extracts of the named plant to cure diabetes and other diseases in the south of Côte d’Ivoire. This study aimed to assess both acute toxicity and hypoglyceamic activity together with performing a comparative study. The acute toxicity was determined...

Author(s): Mamadou Kamagate, N’Goran Mathieu Kouame, Eugène Koffi, Amani Brice Kadja, Koffi Camille, N’Guessan Alain Roland Yao, Eric Balayssac, Therèse Daubrey-Potey, Kanga Sita N&#;zoue and Henri Maxime Die-Kacou