April 2021

Knowledge of hypertension and diabetes comorbid patients about their medication in a municipal hospital in Ghana

Patients with hypertension and diabetes co-morbidity may have medication knowledge and therapy challenges that could impact on patients’ outcomes. The study examines knowledge of medication and therapy among hypertension and Type-2- diabetes mellitus co-morbid patients at a Municipal hospital in Ghana. This study was conducted at the medical outpatient department (OPD) of the Municipal Hospital in Tema (a Harbour...

Author(s): Kwakye, A. O., Buabeng, K. O., Opare-Addo, N. A. M. and Owusu-Dabo, E.  

April 2021

Quality assessment of frequently available mother tinctures in the market by employing standard values

As general awareness for using herbal drugs in today’s health practice is increasing, the world is endorsing extraordinary increase in the consumption of herbal products. This increase in the demand has led to consumers’ dissatisfaction due to substandard products, making the herbal market risky. There is need to set standard that will help to evaluate herbal drugs to ensure formulation of high quality...

Author(s): Mahrukh Malik, Shahzad Hussain, Javeria Arshad Malik, Asia Adil, Sara Nazir and Muhammad Usman Gondal  

April 2021

NONMEM population pharmacokinetic and Monte Carlo dosing simulation of ertapenem in patients with sepsis

An alteration of pharmacokinetics (PK) due to pathophysiological changes in patients with critical illnesses have the impact on the drug levels in plasma, consequently affecting the achievement of pharmacodynamics (PD) targets of antibiotics. The objectives of this study were (i) to determine the population PK, and (ii) to assess the probability of target attainment (PTA) of ertapenem in patients with critical...

Author(s): Sutep Jaruratanasirikul, Napawadee Nopparatana, Apinya Boonpeng, Somchai Sriwiriyajan, Natruethai Kaewpratum, Maseetoh Samaeng and Monchana Nawakitrangsan