African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2220

Table of Content: August, 2020; 14(7)

August 2020

Prevalence and gene sequencing of extended spectrum β-lactamases producing Salmonella enterica serovar. Typhi from South-East Nigeria

Enteric fever is a systemic disease classified into typhoid and paratyphoid fever. Fluoroquinolones and third generation cephalosporins are usually the drugs of choice in the management of Salmonella infections. Previous reports have indicated common occurrence of multi-drug resistance (MDR) including resistance to β-lactams and fluoroquinolones. However, there is paucity of information on the genetic determinants...

Author(s): Nathaniel Ejikeme Onyenwe, Nnabuike Didacus Nnamani, Jude Chidi Okoro, Chioma Nnenna Nwofor and Christiana Jesumirhewe  

August 2020

Assessment of acute and sub-chronic toxicity of Camellia hakodae Ninh leaves aqueous extracts in experimental animals

Camellia hakodae Ninh (CHN) is an ornamental plant of Vietnam, whose extracts is used as a potential phytotherapeutic beverage due to its good improvement in the immune system, reduction of inflammation and assisting the treatment of some chronic diseases. CHN production may be useful for health during this coronavirus epidemic period. This study aimed to evaluate the safety, acute and sub-chronic toxicity of aqueous...

Author(s): Hong Hanh Nguyen, Hoang Ngan Nguyen and Van Cuong Truong  

August 2020

Comparative analysis of biopharmaceutic classification system (BCS) based biowaiver protocols to validate equivalence of a multisource product

Biopharmaceutic classification system (BCS) is a substantial part of drug designing and generic product development and has been accepted as a technique to renounce in-vivo pharmacokinetic evaluation (biowaiver). It appeared to be worthwhile and time-saving by means of in-vitro studies in the presence of biorelevant physiological mediums that mimic not only the predictable solubility but also permeability of the...

Author(s): Farah Khalid, Syed Muhammad Farid Hassan, Madiha Mushtaque, Rabia Noor, Sana Ghayas, Iyad Naeem Muhammad and Fouzia Hassan  

August 2020

Assessment of household knowledge, attitude and practices on disposal methods of expired and unused medicines among residents of Lusaka City, Zambia

Medicines play an important role in treating different diseases and conditions, but when left unused or to expire at home and improperly disposed, they may cause environmental pollution and can be hazardous to health. In this study, assessment of household knowledge attitude and practices on disposal methods of expired and unused medicines among residents was done in selected areas of Lusaka City, Zambia. This was...

Author(s): Martin Kampamba, Martin Nyirenda, Hanzooma Hatwiko, Davies Kampamba and Christabel Nangandu Hikaambo  

August 2020

Pharmacognostic and toxicological evaluation of the leaves of Piper guineense Schum. and Thonn (Piperaceae)

The leaves of Piper guineense Schum. and Thonn (Piperaceae) are used in ethnomedicine for the management/treatment of various diseases. The objective of this study was to establish the pharmacognostic and toxicological profiles of P. guineense to help practitioners in making choices, and to assist scientists involved in the research of the Piper genus. The fresh leaves were examined for their macroscopic and microscopic...

Author(s): Tavs A. Abere ⃰, Mumuni Sumaila and Obi Ifeoma Stephanie  

August 2020

Prescribing pattern of medications prescribed to outpatients based on WHO prescribing indicators in Ethiopia: A systematic review and meta-analysis of observational studies

Poor prescribing pattern is observed and become a serious problem in the world including developing countries. In Ethiopia, several studies showed that health care institutions did not meet WHO prescribing indicators and the prescribing pattern is not satisfactory in the health care institutions. This study aimsto review the prescribing pattern of medications prescribed to outpatients based on WHO prescribing indicators...

Author(s): Wondim Ayenew, Getahun Asmamaw and Atsede Getaneh  

August 2020

Toxicological potential of ethanol extract of stem bark and Croton heliotropiifolius (Euphorbiaceae)

Croton heliotropiifolius is an endemic specie in northeast of Brazil. It is renowned for its medicinal properties, larvicidal, insecticidal and cytotoxic activity. This study evaluated the phytochemical screening of ethanolic extract stem bark of C. heliotropiifolius (EECroton) and the toxicological potential in Swiss albino mice. Phytochemical analysis were performed by thin-layer chromatography. The EECroton at 2000...

Author(s): Willams Alves da Silva, Kristiana Cerqueira Mousinho, Mary Anne Medeiros Bandeira, Marcos Aurélio Santos da Costa, Renatha Claudia Barros Sobreira, Tainá Maria Santos Silva, José Gildo da Silva, Sandrine Maria de Arruda Lima, Luciano Souza de Lima, Roberta M Leite Lima and Sônia Pereira Leite