African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2281

Table of Content: February 2010; 4(2)

February 2010

A comparative study for interpenetrating polymeric network (IPN) of chitosan-amino acid beads for controlled drug release

The paper addresses development of novel pH sensitive interpenetrating polymeric network (IPN) beads composed of chitosan-glycine-glutamic acid cross linked with glutaraldehyde and their use for controlled drug release. A comparative study has been carried out on these IPN beads with the beads that of chitosan, chitosan-glycine and chitosan-glutamic acid cross linked with glutaraldehyde. The beads were characterized by...

Author(s): Manjusha Rani, Anuja Agarwal, Tungabidya Maharana and Yuvraj Singh Negi

February 2010

Ethnobotanical survey of antimalarial plants used in Ogun State, Southwest Nigeria

An ethnobotanical survey of herbal medicine used for treatment of malaria fever in 17 communities in Ogun State, Southwest Nigeria was carried out. According to the results, 38 plant species belonging to 24 families were used in herbal antimalarial recipes. Among the plants mentioned, the most frequently used...

Author(s): O. A. Idowu, O. T. Soniran, O. Ajana and D. O. Aworinde

February 2010

Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva

Salivary nicotine and cotinine are widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and cotinine vary by technique and duration. This study investigated the influence of salivary collection by unstimulation and stimulation technique of the concentration of salivary nicotine and cotinine. It was found that unstimulated technique...

Author(s): N. Robson, A. J Bond and K. Wolff

February 2010

Assessment of antibacterial and cytotoxic activity of some locally used medicinal plants in Sundarban Mangrove Forest Region

Polyalthia longifolia (Annonaceae), Elaeocarpus serratus (Elaeocarpaceae) andTrachyspermum ammi (Umbelliferae) are traditionally employed to cure various health ailments in Bangladesh. Extracts of these medicinal plants were tested for their potential antibacterial activity and cytotoxicity using the disc diffusion method and the brine shrimp lethality tests respectively. Ethanol...

Author(s): Shazid M. D. Sharker and Israt Jahan Shahid

February 2010

In -vitro and -vivo antioxidant activities of aqueous extract of Strychnos henningsii Gilg

Strychnos henningsii Gilg is used traditionally for the treatment of various ailments in southern Africa traditional medicine. The antioxidant and free radical scavenging activity of aqueous extract of this plant was investigated both in vivo and in vitrousing spectroscopic method against 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide anions, hydrogen peroxide (H2O2), nitric oxide (NO), 2,2’-...

Author(s): S. O. Oyedemi, G. Bradley and A. J. Afolayan

February 2010

Anti-ulcerogenic evaluation of root extract of Ficus hispida Linn. in aspirin ulcerated rats

The present study was designed to investigate the anti-ulcer efficacy of methanolic root extract of the Ficus hispida Linn. (FH), which was known to possess various therapeutic properties. The reason for the study was that the known non-steroidal anti-inflammatory drugs (NSAIDs) were full of side effects especially ulceration causes Gastric ulceration an economic loss and a source of welfare concern worldwide....

Author(s): D. Sivaraman and P. Muralidharan

February 2010

Preliminary phytochemical and antimicrobial investigations of leaf extracts of Ochna schweinfurthiana (Ochnaceae)

The antimicrobial activity of the acetone and methanol extracts of the leaves ofOchna schweinfurthiana F. Hoffm. (Ochnaceae) obtained through maceration was evaluated using disc diffusion and Nutrient broth dilution techniques. The microorganisms tested were: Staphylococcus aureus ATCC 021001, Bacillus subtilis NCTC 8236, Escherichia coli NCTC 10418, Salmonella...

Author(s): M. I. Abdullahi, I. Iliya, A. K. Haruna, M. I. Sule, A. M. Musa and M. S. Abdullahi

February 2010

Anti-termite and antimicrobial properties of paint made from Thevetia peruviana (Pers.) Schum. oil extract

Thevetia peruviana (Pers.) K. Schum. seed oil was used to make a surface coating with antifungal, antibacterial and anti-termite properties. The paint exhibited inhibitory activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilisand Candida albicans in a concentration dependent manner. The antibacterial activities were statistically significant (p = 0.05). The repellent action of...

Author(s): P. G. Kareru, J. M. Keriko, G. M. Kenji and A. N. Gachanja