African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2173

Table of Content: January, 2020; 14(1)

January 2020

Formulation and enhancement of dissolution rate of poorly aqueous soluble drug Aceclofenac by solid dispersion method: In vitro study

Solid dispersion technique was successfully used to enhance the dissolution of poorly aqueous soluble drugs aceclofenac. Four carriers Hydroxyl propyl methylcellulose (HPMC), polyvinyl alcohol (PVA), Mannitol and Dextrose in two ratios (1:2, 1:3 w/w) were used to prepare solid dispersion. Eight different formulations were designed by the varying carrier and the drug: Carrier ratio and solvent wetting method was used for...

Author(s): Sumana Neupane and Chhitij Thapa  

January 2020

Histopathological and genetic study on the protective role of β-Carotene on testicular tissue of adult male albino rats treated with titanium dioxide nanoparticles

Titanium dioxide nanoparticles are one of the famous widely produced nanoparticles in the world that are widely used in paints, cosmetics, plastics, pharmaceutical preparations, water treatment and purification and filtration of air. Beta carotene is provitamin A carotenoid with antioxidant and anti-apoptotic activities. The aim of this study is to evaluate the histopathological changes that occur in the testicular...

Author(s): Amira Hamed Mohamed Soliman, Ibrahim Amin Ibrahim, Mohammed Ahmed Shehata and Heba Osama Mohammed  

January 2020

Evaluation of pharmaceuticals in household waste in Senador Canedo, State of Goiás, Brazil

The disposal of pharmaceuticals has become a problem for society and public health and causes risks to the environment. Therefore, the objective of this work was to evaluate the number of pharmaceuticals and the classes of the most discarded pharmaceuticals in household waste in Senador Canedo, Goiás, Brazil. The study was conducted in Senador Canedo, GO, Brazil (16° 42' 28'' S, 49° 5'...

Author(s): Pollyana Dalenogari Costa and Lúcia Maria Moraes