October 2019

Tremendous health benefits and clinical aspects of Smilax china

A lot of species of Smilax known as Baqia in China are used in folk medicine for various purposes. Smilax china L., is a small vine that grows in the southern parts of China, known as Jin Gang Ten, which has a long history of indigenous use in China. S. china consists of fat, saponins, glucosides, gum, starch, flavonoids, tannins, and alkaloids. S. china has been used in traditional Chinese medicine because it has...

Author(s): Mohamad Hesam Shahrajabian, Wenli Sun, and Qi Cheng,  

October 2019

Effect of the anticancer drug tamoxifen on chronic toxoplasmosis in experimentally infected rats

Toxoplasma gondii is an opportunistic parasite that can cause severe disorders in infants and pregnant women and can also be lethal in immunologically compromised individuals. During unfit host immune conditions, and as a consequence to latent stage opportunity, the protozoan stimulates serious infection, and signifies higher morbidity and mortality including humans with Acquired Immuno-Deficiency Syndrome (AIDS) or...

Author(s): Rabab Fawzy Selem, Gehan Abdel Rahman Rashed, Ashraf Mohamed Abdel Khalek Barakat, Hasan Mohamed Ali Elfadaly, Boshra EL-sayed Talha Hussien, Hemat Salah Mohamed, Marwa Mohamed Nageeb and Ahlam Farag Moharm  

October 2019

Prevalence and indication of gabapentin and pregabalin prescriptions among adults in King Abdulaziz Hospital in Makkah AL-Mukarramah, KSA

Gabapentin and pregabalin prescribing have increased substantially over the recent years. Some evidence supports that gabapentin and pregabalin use in non-neuropathic pain disorders indicates they are less effective than several other licensed non-opioid analgesics. On the other hand, other studies have shown that those drugs are to be beneficial in the treatment of non-neuropathic pain and improves the analgesic...

Author(s): Salma Alotaibi, Arwa Alotaibi, Ashwaq Almqati, Khloud Alotaibi, Atyaf Bogar and Yosra Alhindi  

October 2019

Pharmaceutical polymorphisms and its influence on the dissolution profile of two pioglitazone brands

1Pharmacognosy Laboratory,Faculty of Chemical Sciences, Juarez Durango State University, Mexico. 2Technology and health laboratory, Academic Coordination Altiplano Region, Autonomy University of San Luis, Potosi, Mexico.  

Author(s): Eduardo Lozano Guzmán, Saúl Alejandro Aguirre Rentería, María Guadalupe Nieto Pescador, Maribel Cervantes Flores, Ángel Antonio Vértiz Hernández and  Francisco Javier Moreno Cruz  

October 2019

Evaluation of hypoglycemic activity and safety of Carica papaya seed extracts in alloxan-induced diabetic mice

Carica papaya is used for the treatment of many diseases such as stomach upsets, diarrhoea, bilharzia, diabetes. The study aims to evaluate the safety and hypoglycemic potential effect of Carica papaya seeds on alloxan induced diabetic mice. DCM extracts were examined for the presence of terpenoids, flavonoids, steroids, phenols, tannins and alkaloids. Toxicity profile was established at 5, 50, 200, 300 and 2000 mg/kg...

Author(s): Samuel P. Kagame, , Nicholas Mwikwabe, Peter Mwitari and Moses Gichua