African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: October 2009; 3(10)

October 2009

Pharmacological and nutritional activities of potato anthocyanins

Colored potatoes are due to the accumulation of anthocyanins in the stem tubers. The strong antioxidative activity of potato anthocyanins results from the promotion effects of the anthocyanins on the activities of the antioxidant enzymes and is positively correlated to the anthocyanin content, which derives several important pharmacological actions. Both the antioxidative strength and anti-influenza virus activity of...

Author(s): Chang Ling Zhao, Hua Chun Guo, Zhi Yuan Dong and Qing Zhao

  • Article Number: 27B997936594

October 2009

Kinetics of acetylcholinesterase inhibitory activities by aqueous extracts of Acacia nilotica (L.) and Rhamnus prinoides (L’Hér.)

Acetylcholinesterase (AChE) is a key target in the treatment of Alzheimer’s disease (AD). We studied the potential anti-AChE activities of Acacia nilotica(Leguminosae) and Rhamnus prinoides (Rhamnaceae) plants that have previously been shown to affect central nervous system activities. Sonicated aqueous extracts of A. nilotica and R. prinoides displayed significant AChE...

Author(s): Catherine Megan Crowch and Edward Jonathan Okello

  • Article Number: 2F688BC36625

October 2009

In vitro antimicrobial activity of Cryptolepis sanguinolenta (periplocaceae)

The aim of the present study was to investigate in vitro, the effect of three different preparations of Cryptolepis sanguinolenta, obtained from 2 mg/ml each of 70% ethanol, hot and cold aqueous extract, as antimicrobial agents using agar diffusion method. The microbes used in this study consisted of one strain of Salmonellatyphimurium, two strains each of Proteus mirabilis, Pseudomonas...

Author(s): Felix C. Mills-Robertson, Frederick A. Aboagye, George Duker-Eshun, Sylvester Kaminta and Samuel Agbeve

  • Article Number: 5DDBE2E36659

October 2009

Hypoglycaemic effect of aqueous stem extract of Anisopus mannii in normal rats

The hypoglycaemic effect and acute oral toxicity of graded doses of aqueous extract of Anisopus mannii was investigated in rats. The revised limit dose test of Up and Down procedure was used to determine the acute oral toxicity of the plant. The result revealed that the Median lethal dose of the plant is greater than 3000 mg/kg body weight. The treatment of the rats with varying doses of the plant extract for...

Author(s): D. Sani, S. Sanni and S.I. Ngulde

  • Article Number: 5D46FBC36683

October 2009

Effect of the aqueous seed extract of Persea americana mill (Lauraceae) on the blood pressure of sprague-dawley rats

The aqueous seed extract (AE) of Persea americana Mill (Lauraceae) is used by some herbal medicine practitioners in Nigeria for the treatment of hypertension. We investigated its effects on the mean arterial pressure (MAP) and Heart Rate (HR) of naïve and 260 mg/kg/day x 10 days pretreated rats. Naïve rats were given bolus injections of (a) - AE (240, 260, 280 mg/kg); (b) - 2 µg/kg of...

Author(s): Ogochukwu N. Anaka, Raymond I. Ozolua and Stephen O. Okpo

  • Article Number: FEE5B4936707

October 2009

In-vitro evaluation of the pharmaceutical quality of some ibuprofen tablets dispensed in Nigeria

The purpose of this study was to determine the pharmaceutical quality of some Ibuprofen tablets dispensed in Nigerian. 19 different brands of Ibuprofen tablets were purchased from pharmacies and open markets in 3 states in Nigeria. The organoleptic and physicochemical properties of these Ibuprofen tablets were assessed according to British Pharmacopoeia (BP), and unofficial standards as recommended by the manufacturers....

Author(s): Florence E. Eichie, Ikhuoria M. Arhewoh and Oliver C. Ezeobi

  • Article Number: B5359DC36730

October 2009

Informant consensus selection method: A reliability assessment on medicinal plants used in north western Nigeria for the treatment of diabetes mellitus

In this study, the reliability of informant consensus as a method of selecting medicinal plants for pharmacological screening was tested. Ten plants were selected based on the method and screened for antidiabetic properties using animal experimental model of the disease. The plants were selected from a list of medicinal plants obtained from a botanical survey of the region. A correlation between the two sets of data...

Author(s): E. U. Etuk and B. J. Mohammed

  • Article Number: F4FC6CC36750

October 2009

Effect of aqueous extract of Chrysophyllum cainito leaves on the glycaemia of diabetic rabbits

Chrysophyllum cainito is a plant recognized by the traditional healers of Aboudé-Mandéké, a village in the Department of Agboville (Côte-d’Ivoire), as having antidiabetic properties. The aim of this study is to evaluate, experimentally, the effect of an aqueous decoction of the plant’s leaves that we called C. cainito, on rabbits induced with alloxane, a diabetogenic...

Author(s): N&#;guessan Koffi, Amoikon Kouakou Ernest, Tiébré Marie-Solange, Kadja Beugré and Zirihi Guédé Noël

  • Article Number: B4EABF436853