September 2009
Review on the importance of documenting ethnopharmacological information on medicinal plants
This paper reviews and discusses the importance of documenting ethnopharmacological information on medicinal plants. The literature review was done by collecting relevant information from journal articles, workshop proceedings, books and electronic resources. The review sums up the importance of documenting the indigenous traditional knowledge on medicinal plants as being a vehicle for; (i) preserving cultural...
September 2009
Possible benefits of micronutrient supplementation in the treatment and management of HIV infection and AIDS
Recently, several reports have indicated that individuals living with HIV/AIDS undergo a condition of chronic oxidative stress with a resultant decline in nutritional antioxidants and other micronutrients. It has also been reported that these micronutrient deficiencies interfere with immune functions, weaken epithelial integrity, contribute to oxidative stress and enhance HIV disease progression. Reports from...
September 2009
The role of vaccines in elimination and global eradication of measles- a review of literature
This review summarizes the role of vaccines in elimination and global eradication of measles-a review of literature. Measles eradication is defined as the interruption of measles transmission worldwide as a result of deliberate efforts; intervention methods may no longer be needed. It represents the sum of successful elimination efforts in all countries. Indeed, measles transmission has been interrupted in several...
September 2009
Comparative utilization of visual, potentiometric titrations and UV spectrophotometric methods in the determination of Ibuprofen
The accuracy and reliability of the analytical results are critical in ensuring quality, safety, and efficacy of pharmaceutical products. However, to ensure these criteria, the choice of appropriate analytical method is required. This study sets out to compare the efficacy of visual, potentiometric titrations and UV spectrophotometric methods in the determination of the quality of Ibuprofen tablets in Nigeria. Eight...
September 2009
Depletion of parasitaemia by halofantrine hydrochloride and artemether in rats infected with African trypanosomes
Two antimalarial drugs; Halofantrine HCl and Artemether whose mechanism of action has been shown to depend on the disruption of the red blood cells during malarial infections were investigated for possible trypanocidal activity in vivo. Pre-treatment with Artemether before infection with the parasite had no effect on infected rat when compared to the control. Treatment at the early stage of infection extended the...
September 2009
Calcium channel blocking activities of Withania coagulans
The effects of crude methanolic extract of Withania coagulans (Wc.cr) were studied for possible calcium channel blocking activities in rabbit’s jejunum preparations at different doses. Potassium chloride (KCl) induced contractions were also inhibited by the Wc.cr extract suggesting calcium channel blocking activity. Calcium channel blocking activity was confirmed by the right shift in the dose response...
September 2009
Evaluation of the effect of intrahippocampal injection of leptin on spatial memory
Leptin is a peptide hormone secreted by adipose tissue. Some studies have suggested that leptin may affect learning and memory. The hippocampus has been implicated in many learning and memory functions including spatial memory. The present study is scheduled to investigate the effect of intrahippocampal (IH) injection of different doses of leptin on spatial memory formation. 40 male rats were divided into 4 groups in...
September 2009
Prevalence of adverse drug events in the consultation centre of Ibn Sina
Incidence of adverse drug reactions [ADRs] leads to many conflicting discussions about patients safety in many countries. It has been shown that ADRs are more frequent in outpatient department rather than indoors. We wanted to find out if there is similar situation in Morocco as well. Due to lack of National data we investigated the incidence of ADRs in patients of teaching hospital Ibn Sina in...
September 2009
Phytochemical and pharmacological evaluation of Solanum nigrum Linn.
The present investigation designed to evaluate the phytochemical and pharmacological activity of ethanolic extract of Solanum nigrum in experimental animal models. The ethanolic extract of S. nigrum was used in three different doses (100, 200 and 300 mg/kg bw) to evaluating anti-inflammatory and anti-convulsant activity by employing carrageenan paw edema and Supramaximal electric shock (MES) methods....
September 2009
Compositions and comparison of the leaf and stem essential oils from Nigerian Hypoestes phyllostachya ‘rosea’ p. Beau. [acanthaceae]
Leaf and stem volatile oils were obtained differently from Hypoestes phyllostachya ‘Rosea’ (Acanthaceae) in 0.36 and 0.13% yields, respectively. GC-MS analyses revealed 38 compounds are responsible for 99.86% of the leaf oil, and 26 compounds make-up 99.89% of the stem oil. Identified compounds were 26 in leaf, which make-up 93.43% of it; 21 identified in stem, which represent 90.45% of it. Leaf oil is...
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