African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2183

Table of Content: September 2010; 4(9)

September 2010

Is there a need for ototoxicity monitoring in patients with HIV/AIDS?

This paper reviews published research on hearing loss in adults with HIV/AIDS with a special focus on the possibility of ototoxicity of the medications used in clinical management of this population. Findings from all published papers on the subject, which include but are not limited to case reports, cross-sectional, as well as longitudinal studies where ototoxicity monitoring of patients on antiretroviral therapy (ART)...

Author(s): Khoza-Shangase Katijah

  • Article Number: 9180A9C26919

September 2010

Healing the body and soul: Traditional remedies for “magical” ailments, nervous system and psychosomatic disorders in Northern Peru

Mal aire (bad air), mal viento (bad wind), susto and espanto (fright), mal ojo (evil eye) and envidia (envy) are seen as very common illnesses in Andean society. The Western concept of “psychosomatic disorders” comes closest to characterizing these illnesses. Treatment in many cases involves the participation of the patient in a cleansing ceremony. In...

Author(s): Rainer W. Bussmann, Ashley Glenn and Douglas Sharon

  • Article Number: D9765AB26983

September 2010

Assessing the polyphenolic, nutritive and biological activities of acetone, methanol and aqueous extracts of Rumex sagittatus Thunb.

The nutritional, phytochemical and antioxidant activities of acetone, methanol and aqueous extracts of the leaves of Rumex sagittatus Thunb were investigated using standard analytical methods in order to assess the therapeutical potential of the leaves of this plant. The proximate analysis showed that the leaves contained appreciable amount of ash, crude protein, lipids, fibre and carbohydrates. Elemental...

Author(s): F. O. Jimoh, A.  A. Adedapo and A. J. Afolayan

  • Article Number: 23809C627025

September 2010

Antihypercholesterolemia property and fatty acid composition of mardi-produced virgin coconut oils

Virgin coconut oil (VCO), or in Malays known as ‘minyak kelapa dara’, has gain a lot of attention recently due to various medicinal values. The aim of the present study was to evaluate the effect of feeding two types of VCOs, VCOA (produced via a standard drying method) or VCOB (prepared via fermentation process), that were produced by Malaysia Agriculture Research and Development Institute (MARDI)...

Author(s): Z. A. Zakaria, Z. Ahmad, M. N. Somchit, A. K. Arifah, H. M. Khairi, M. R. Sulaiman, L. K. Teh, M. Z. Salleh and K. Long

  • Article Number: 46CFFE127094

September 2010

Phytochemical screening and antimicrobial activities of Euphorbia balsamifera leaves, stems and root against some pathogenic microorganisms

Plants and plant-based products are the bases of many of the modern pharmaceuticals we use today for various ailments. The objective of the study is to determine the bioactive chemical constituents and to evaluate extracts of Euphorbia balsamifera leaves, stem and root for in vitro antimicrobial activities by seagar dilution method. Phytochemical analysis of the crude extracts of the plant parts...

Author(s): A. S. Kamba and L. G. Hassan

  • Article Number: 0EDBBEE27130

September 2010

Effect of methionine on hepatic indices in male Wistar rat dosed to acetaminophen formulation

Studies’ reports in both humans and experimental animals have supported the use of methionine as an effective antidote to counteract the manifestation of hepatotoxicity, which is a common occurrence of acetaminophen at overdose levels of exposure. This study was embarked on to test the hepatoprotective effect of methionine in acetaminophen tablets, produced by a leading paracetamol brand in Nigeria especially in...

Author(s): A. A. Iyanda, J. I. Anetor, F. A. A. Adeniyi and C. I. Iheakanwa

  • Article Number: FC4CBDC27164

September 2010

Effects of short-term exercise on heart-rate blood pressure oxidative stress paraoxonase activity and lipid hydroperoxide

This study inquired the effects of short-term exercise on heart-beats, blood pressure, total anti-oxidative capacity (TAC), total oxidative stress (TOS), lipid hydro-peroxide (LOOHs) and Paraoxonase (PON) in football players. 22 male football players, who perform exercise regularly at least three times a week and two hours a day, participated in this study on voluntary basis. Heart-beats, systolic and diastolic blood...

Author(s): Özdağ Selçuk

  • Article Number: A94369527187

September 2010

Traditional knowledge on ethno-medicinal uses prevailing in tribal pockets of Chhindwara and Betul Districts, Madhya Pradesh, India

The present paper deals with the traditional knowledge of traditional herbal healers of Chhindwara and Betul districts of Madhya Pradesh, India regarding the use of plants for the treatment of various diseases prevalent in the tribal pockets. The herbal healers of these region use plant/plant parts of their suitable preparation for treating various ailment. Information collected from traditional tribal healers, medicine...

Author(s): Nath Vijendra and Khatri Pavan Kumar

  • Article Number: 94D18EF27229

September 2010

The prohibitive effect of lactoperoxidase system (LPS) on some pathogen fungi and bacteria

Lactoperoxidase is a peroxidase enzyme found in milk. This enzyme has antimicrobial and antioxidant properties. It is fairly heat resistant and was widely used as an indicator of over pasteurization of milk. In the present study, bovine lactoperoxidase (LPO) was purified from skimmed milk using amberlite-CG-50-H+ resin, CM-sephadex-C-50 ion-exchange chromatography and sephadex-G-100 gel filtration...

Author(s): Melda Sisecioglu, Ekrem Kirecci, Murat Cankaya, Hasan Ozdemir, Ilhami Gulcin, and Ali Atasever

  • Article Number: A48DF4027261

September 2010

In vitro and in vivo evaluation of two sustained release formulations of diltiazem HCl

In the present study, two sustained release solid and semi-solid matrices were developed using Hydroxypropyl methyl cellulose (HPMC) and Gelucire derivative, Gelucire 50/30. The purpose of the study was in vitro and in vivo correlation of these two sustained release formulations with SR capsules available in market and to know how long the preparation containing HPMC and Gelucire work in the body as...

Author(s): Muhammad Rafiq, Abdul Wahab, Nisar-ur-Rehman, Abid Hussain and Said Muhammad

  • Article Number: 2C91E7627292