September 2023

Assessment of the in vivo acute toxicity of aqueous extracts of artavol® antimalaria herbal tea

Acute toxicity testing plays a pivotal role in the initial safety assessment of products. It examines the effects of a single or multiple doses of a product administered to animals or taken by humans within a 24-hour period. This test holds particular importance in determining the toxic characteristics of products intended for use in humans, animals, and agriculture. Despite the availability of numerous herbal medicinal...

Author(s): Joseph Oloro, Amon A. Ganafa, Oscar O. P’okello, James M. Mucunu and Timothy E. Maitho

September 2023

Hydrocotyle bonariensis Comm ex Lamm (Araliaceae) leaves effects on rabbit’s blood pressure and electrocardiogram

Hydrocotyle bonariensis Comm ex Lamm (Araliaceae) is traditionally used to treat various pathologies like hypertension. This work aims to evaluate the impact of hydro-ethanolic extract of its leaves on the blood pressure and cardiac activity of rabbits, and then to compare its hypotensive effect to conventional hypotensives. Intravenous injection of the hydro-ethanolic leaf extract (10; 20; 40; 80 and 160 mg /kg body...

Author(s): Komla Kaboua, Tcha Pakoussi, Aklesso Mouzou, Balakiyém Kadissoli, Mindede Assih, Aboudoulatif Diallo, Patrick BOIS and Kwashie Eklu-Gadegbeku