This study aimed to analyze the chemical composition and evaluate the antibacterial activity of essential oils and modulator of Croton heliotropiifolius Kunth and Croton blanchetianus Baill. The oils were obtained with distilled water and their components identified with GC/MS. Eucalyptol (16.9%), β-caryophyllene (15.9%) and germacrene-D (14.5%) for C. heliotropiifolius and cedrol (28.4%), eucalyptol (17, 4%) and α-pinene (10.5%) for C. blanchetianus were observed. The antimicrobial activity and minimum inhibitory concentration (MIC) was determined by the diffusion method and microdilution with standard bacteria Gram positive and negative. Preliminary results of the antibacterial activity showed that both oils were more effective against Gram-positive strain of Bacillus cereus. When verifying the minimum inhibitory concentration, it was observed that the essential oil of C. heliotropiifolius showed inhibitory activity only for the lineage multiresistance Staphylococcus aureus (MR 358), 512 μg/mL with MIC. For the essential oil of C. blanchetianus, the result was significant for S. aureus with an MIC of 64 mg/mL. The oil of C. blanchetianus potentiated the antibiotic amikacin, kanamycin and gentamycin against B. cereus strain, showing a synergistic effect.
Key words: Phytochemistry, antimicrobial, bacterial resistance, secondary metabolites.
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