African Journal of
Plant Science

  • Abbreviation: Afr. J. Plant Sci.
  • Language: English
  • ISSN: 1996-0824
  • DOI: 10.5897/AJPS
  • Start Year: 2007
  • Published Articles: 688

Full Length Research Paper

Pharmacological screening of Nigerian species of Musanga cecropioides R. Br ex Teddlie (Moraceae) in rodents as anti-hypertensive

Senjobi C. T.1*, Ettu A. O.1 and Gbile Z. O.2    
1Department of Biology, School of Science, Tai Solarin College of Education, Omu, Ijebu-Ode, Ogun State, Nigeria. 2Department of Microbiology, Faculty of Science, Olabisi Onabanjo University, Ago-Iwoye, Ogun State, Nigeria.  
Email: [email protected]

  •  Published: 27 April 2011

Abstract

A study was carried out to screen Musanga cecropioides R. Br ex Teddlie (Moraceae) for anti-hypertensive and analgesic properties using smooth and skeletal muscles in rodents in an attempt to evaluate the efficacy of medicinal plants and further search for novel structure. M. cecropioides locally known as “umbrella tree”, Aga (Yoruba), Agar Umbrella (English), Parasolier (French) has been screened for anti-hypertensive and analgesic properties. The aqueous extract of M. cecropioides used in this investigation was prepared using the smooth and skeletal muscles in rodents. Aqueous extract of M. cecropioides was found to contain ingredients that were active as analgesic, anti-hypertensive and spaspogenic.

 

Key words: Musanga cecropioides (Moraceae), analgesic, anti-hypertensive.

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