African Journal of
Plant Science

  • Abbreviation: Afr. J. Plant Sci.
  • Language: English
  • ISSN: 1996-0824
  • DOI: 10.5897/AJPS
  • Start Year: 2007
  • Published Articles: 761

Full Length Research Paper

Cytotoxicity study on Maerua pseudopetalosa (Glig and Bened.) De Wolf tuber fractions

Manal A. Ibrahim*
  • Manal A. Ibrahim*
  • Department of Botany, Faculty of Science and Technology, Omdurman Islamic University, Sudan.
  • Google Scholar
El Bushra E. El Nur
  • El Bushra E. El Nur
  • Department of Botany, Faculty of Science, University of Khartoum, Sudan.
  • Google Scholar

  •  Received: 13 July 2015
  •  Accepted: 12 October 2015
  •  Published: 30 December 2015


Adoum OA (2009). Determination of toxicity levels of some savannah plants using brine shrimp tests (BTS). Bayero J. Pure Appl. Sci. 2(1):135-138.


Ahammadsahib KI, Hollingworth RM, McGovern PJ, Hui YH, McLaughlin JL (1993). Inhibition of NADH: ubiquinone reductase (mitochondrial complex I) by bullatacin, a potent antitumor and pesticidal Annonaceous acetogenin. Life Sci. 53:1113-1120.


Ahmad B, Ali N, Shumaila B, Choudhary MI (2009). Biological activities of aerial parts of Tylophora hirsuta Wall. Afr. J. Biotechnol. 8(18):4627-4631.


Almeida PA, Silva TMS, Echevarria A (2002). Mesoionic 5-alkyl-1,3-dithiolium-4-thiolates: Synthesis and brine shrimp toxicity. Heterocycl. Comm. 8:593-600.        


Anderson JE, Goetz CM, McLaughlin JL, Suffness M (1991). A blind comparison of simple bench-top bioassay and human tumour cell cytotoxicities as antitumor prescreens. J. Phytochem. Anal. 2:107-111.        


Bastos ML, Lima MR, Conserva LM, AndradeVS, Rocha EM, Lemos RP (2009). Studies on the antimicrobial activity and brine shrimp toxicity of Zeyheria tuberculosa (vell.) Bur. (Bignoniaceae) extracts and their main constituents. Ann. Clin. Microbiol. Antimicrob. 8:16.


Bose V, Bala V, Ghosh NT, Gunasekaran K, Rahman A (2011).Antinociceptive, cytotoxic and antibacterial activities of Cleome viscose leaves. Rev. Bras. Farmacogn. 21(1):45-51.


Burkill HM (1985).The useful plants of West Tropical Africa. Royal Botanical Garden.1(1):18-26.


Doka IGM (2001). Some medicinal plants of Western Kordofan folklore and phytochemical screening. MSc. Thesis. Faculty of Science Unv. Of Khartoum, Sudan. pp. 18.


Harborne JB (1998). Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 3rd Edn., Chapman and Hall, London. pp. 302.


Henry AJ (1948). The toxic principle of Courbonia virgata: Its isolation and identification as a tetramethylammonium salt. Birth. J. Pharmacol. 3:187.


Hostettmann K (1991). Methods in Plant Biochemistry: Assays for Bioactivity. Academic Press, London. UK. 6:360.


Isidrov VA, Czyzewska V, Jankowsk M, Bakier S (2011). Determination of royal jelly acid in honey. J. Food Chem. 124:387-391.


Kalinovsky T, Waheed M, Nusrath W, Ivanov V, Niedzwiecki A, Rath M (2005). Modulation of N-methyl-N- nitrosourea induced mammary tumors in Sprague-Dawley rats by combination of lysine,proline, arginine, ascorbic acid and green tea extract. J. Breast Cancer Res. 7:291-295 


Kennedy GL (1986).Biological effects of acetamides and formamides and their monomethyl and dimethyl derivatives. J. Crit. Rev. Taxicol. 7(2):129-182.


Mackeen MM, Ali AM, Lajis NH, Kawazu K, Hassan Z, Amran M, Habsah M, Mooi LY, Mohamed SM (2000). Antimicrobial, antioxidant, antitumour-promoting and cytotoxic activities of different plant part extracts of Garcinia atroviridis Griff. Ex T. Anders. J Ethnopharmacol. 72:395-402.


McLaughin JL, Rogers LL (1998). The use of biological assays to evaluate botanicals. J. Drug Inform. 32:513-524.


Mclaughin JL, Chang CJ, Smith DL (1991). "Bench – Top" Bioassays for discovery of bioactive natural products: an update. Stud. Nat. Prod. Chem. 9:383-409.


Meyer BN, Ferrigni NR, Putnam JE, Jacobsen LB, Nichols DE, McLaughlin JL (1982). Brine shrimp: A convenient general bioassay for active plant constituents. Planta Med. 45:31-34.        


Mojica E, Jose R (2007). Bioactivity study of Barringtonia asiatica (L.) Kurz. seed aqueous extract in Artemia salina. Int. J. Bot. 3(3):325-328.


Moshi MJ, Cosam JC, Mbwam BOH, Kapingu M, Nkunsya MHH (2004). Testing beyond ethnomedical claims: Brine shrimp lethality of some Tanzanian plants. J. Pharmaceut. Biol. 42:547-551.


Moshi MJ, Mbwambo ZH, Nodo RS, Masmba PJ, Kamuhabwa A, Kapingn MC, Thomas P, Richard M (2006). Evaluantion of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicines. Afr. J. Tradit. Complement. Altern. Med. 3:48-58.


Ortsater H (2011). Arachidonic acid fights palmitate :New insights into fatty acid toxicity in β-cells. J. Clin. Sci. 120:179-181.


Padmaja R, Arun PC, Prashanth D, Deepak M, Amit A, Anjana M (2002). Brine shrimp lethality bioassay of selected Indian medicinal plants. J. Fitoterapia. 73(6): 508-510.


Parra AL, Yhebra RS, Sardinas IG, Buela LI (2001). Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50avalue) in mice to determine oral acute toxicity of plant extracts. J. Phytomed. 8(5):395-400.


Pisutthanan S, Plianbangchang P, Pisutthanan N, Rvanruay S, Muanrit O (2004). Brine shrimp Lethality. Activity of Thia medicinal plants in the family Meliaceae. Naresuan Univ. J. 12:13-18.


Rajesh P, Selvamani P, Lath S, Saraswathy A, Rajesh VK, (2009). A review on chemical and medicobiological applications of capparidaceae family. J. Pharmacogn. 31(6):378-387.


Ronald HA (1997). Gas Chromatography Mass Spectroscopy: Handbook of Instrumental Techniques for Analytical Chemistry. pp. 609-611.


Sani D, Sanni S, Ngulde SI (2009). Phytochemical and antimicrobial screening of the stem aqueous extract of Anisopus mannii. J. Med. Plant Res. 3:112-115.


Solis PN, Wright CW, Anderson MM, Gupta MP, Phillipson JD (1993). A microwell cytotoxicity assay using Artemia salina. Plant. Med. 59:250-252.


William F H, Mclean G, Blunden G, Jeweres K (1996). Quaternary ammonium compounds in the Capparaceae. Biochem. Syst. Ecol. 24(5):427-434.


Zani CL, Chaves PPG, Queiroz R, Mendes NM, Olivii AB (1995). Brine shrimp lethality assay as a prescreening system for anti-Trypanosoma crusi. J. Phytomed. 2:47-50.