The United States, as a world power, participates as an Intrusive power in all regional orders especially West Africa. One of its main strategies is to organize and exploit its relations with regional powers in regulating regional order. In this wise, West Africa has become a very important region in the international order in which it accommodated regional actors that captured United States of America’s attention to regulate the present order. From this point of view, Nigeria is a regional player that plays a very big role in Africa and particularly in West Africa. It has decades of history with US as a strategic ally especially in West Africa. This article attempts to look into Nigeria’s role in US security strategy in the region. This top-ic has never been given a grave attention in the international relations’ literature particularly in the Iran’s literature. There is little agreement among scholars on the impact and implication of Nigeria’s role in US security strategy towards the region in curbing insecurities. We argued that in order for US to protect its geo-strategic, geo-political, geo-economic interest and stra-tegic rivalry that are taking place in the region, US balances and counter balances other pow-ers by taking Nigeria a strategic partner to contain their expansion. In this regard, the conflu-ence of two variables in the Nigerian geopolitics particularly in its maritime geopolitics in the Atlantic with its geoeconomics in the field of oil production and other strategic resources have bestowed upon Nigeria a special position in America’s regional security strategy.

Keywords: Nigeria, US, security strategy, West Africa, regional order.