Clinical Reviews and Opinions

  • Abbreviation: Clin. Rev. Opinions
  • Language: English
  • ISSN: 2141-2553
  • DOI: 10.5897/CRO
  • Start Year: 2009
  • Published Articles: 42

Review

Platelet-mediated clumping adhesion phenotypes of P. falciparum-infected erythrocytes: A review

Frank G Onyambu
  • Frank G Onyambu
  • Department of Chemistry and Biochemistry, Moi University P.O. Box 3900 Eldoret, Kenya.
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Stephen B Tanui
  • Stephen B Tanui
  • Moi Teaching and Referral Hospital, P.O. Box 3 Eldoret, Kenya.
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Dominic S. O. Alwala
  • Dominic S. O. Alwala
  • Moi Teaching and Referral Hospital, P.O. Box 3 Eldoret, Kenya.
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Kiptanui Chebii
  • Kiptanui Chebii
  • Department of Human Pathology, Moi University P.O. Box Eldoret, Kenya.
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Bethwel K. Kigen
  • Bethwel K. Kigen
  • Moi Teaching and Referral Hospital, P.O. Box 3 Eldoret, Kenya.
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  •  Received: 31 July 2015
  •  Accepted: 28 April 2017
  •  Published: 31 July 2017

References

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Arman M, Rowe JA (2008). Experimental conditions affect the outcome of Plasmodium falciparum platelet-mediated clumping assays. Malar J. 7(1):243.
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McMorran BJ, Marshall VM, de Graaf C, Drysdale KE, Shabbar M, Smyth GK, Corbin JE, Alexander WS, Foote SJ (2009). Platelets kill intraerythrocytic malarial parasites and mediate survival to infection. Science 323(5915):797-800.
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McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, Smith C, Mitiku C, Beeson JG, Burgio G, Foote SJ (2012). Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum. Science 338(6112):1348-1351.
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Pain A, Ferguson DJ, Kai O, Urban BC, Lowe B, Marsh K, Roberts DJ (2001). Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria. Proceed. Natl. Acad. Sci. 98(4):1805-1810.
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Robinson BA, Welch TL, Smith JD (2003). Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genome. Mol. Microbiol. 47(5):1265-1278.
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Rowe A, Berendt AR, Marsh K, Newbold CI (1994). Plasmodium falciparum: A family of Sulphated Glycoconjugates Disrupts Erythrocytes Rosettes. Exp. Parasitol. 79:506-516.
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Rowe JA, Claessens A, Corrigan RA, Arman M (2009). Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. Expert Rev. Mol. Med. 11:e16.
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Senczuk AM, Reeder JC, Kosmala MM, Ho M (2001). Plasmodium falciparum erythrocyte membrane protein 1 functions as a ligand for P-selectin. Blood 98(10):3132-3135.
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Srivastava K, Cockburn IA, Swaim A, Thompson LE, Tripathi A, Fletcher CA, Shirk EM, Sun H, Kowalska MA, Fox-Talbot K, Sullivan D (2008). Platelet factor 4 mediates inflammation in experimental cerebral malaria. Cell Host Microbe 4(2):179-187.
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Wassmer SC, Taylor T, MacLennan CA, Kanjala M, Mukaka M, Molyneux ME, Grau GE (2008). Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria—possible modulation in vivo by thrombocytopenia. J. Infect. Dis. 197(1):72-78.
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World Health Organization (WHO) (2016). World Malaria Report 2016. Available at: 

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