July 2010

Molecular phylogeny of Bulinus (Gastropoda: Planorbidae) reveals the presence of three species complexes in the Albertine Rift freshwater bodies

  In this study, partial mitochondrial DNA cytochrome oxidase subunit I (mtCOI) sequences (612 bp) of Bulinus snails sampled from 31 freshwater bodies in the Albertine Rift were analyzed to investigate the extent of genetic variation and phylogenetic relationships. Bayesian phylogenetic inferences clustered the samples into three species groups;Bulinus truncatus/ tropicus, Bulinus...

Author(s): A. Nalugwa, A. Jørgensen, S. Nyakaana and T. K. Kristensen

July 2010

Iron starvation induces expression of a putative xylanase gene in Salmonella enterica subsp. enterica serovar Enteritidis mini-transposon5 lacZ1 mutants

  In this study, Salmonella enterica subsp. enterica serovar Enteritidis mini-transposon5 lacZ1 mutant strains induced under iron starvation were analyzed. Inverse polymerase chain reaction (IPCR) was used to isolate iron starvation-induced DNA fragments upstream of mini-Tn5 (containing a promoter-less lacZ gene) insertion in S. entericasubsp. enterica serovar...

Author(s): Kazhila C. Chinsembu and André Faul

July 2010

The frequency of Y chromosome microdeletions in infertile men from Chennai, a South East Indian population and the effect of smoking, drinking alcohol and chemical exposure on their frequencies

  The aims of the study were to estimate the frequency of Y chromosome microdeletion in infertile men from a new geographical ethnic region, Chennai, South East India, to explore the effect of smoking, alcohol drinking, chemical exposure and cellular chromosomal aberration on the frequency of infertility in 34 azoospermia and 55 oligospermia patients. The frequency of Y chromosome microdeletion was estimated...

Author(s): V. G. Abilash, Radha Saraswathy and K. M. Marimuthu

July 2010

Deletion of derivative ABL, BCR or ABL-BCR fusion gene is associated with shorter disease free survival in CML patients

  Chronic myeloid leukemia (CML) is characterized by formation of the BCR/ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22. However, deletions of the derivative 9 chromosome [der (9)] in10 - 15% of CML patients with a standard Ph translocation as well as > 30% of CML patients with a variant Ph translocation may have verse prognosis....

Author(s): Beena P. Patel, Pina J. Trivedi, Manisha M. Brahmbhatt, Sarju B. Gajjar, Ramesh R. Iyer, Esha N. Dalal, Shilin N. Shukla and Pankaj M. Shah