International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 535

Case Report

Microscopic thymoma accompanying simple thymic hyperplasia

Elif U. Akyildiz
  • Elif U. Akyildiz
  • Department of Pathology, Uludag University School of Medicine, Gorukle, Bursa, Turkey.
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Hale Demir
  • Hale Demir
  • Departments of Pathology, CerrahpaÅŸa School of Medicine, Istanbul University, Istanbul , Turkey.
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Ahmet Demirkaya
  • Ahmet Demirkaya
  • Thoracal Surgery, CerrahpaÅŸa School of Medicine, Istanbul University, Istanbul , Turkey.
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Canan Akman
  • Canan Akman
  • Radiology, CerrahpaÅŸa School of Medicine, Istanbul University, Istanbul , Turkey.
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Buge Oz
  • Buge Oz
  • Department of Pathology, Uludag University School of Medicine, Gorukle, Bursa, Turkey.
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Nil U. Comunoglu
  • Nil U. Comunoglu
  • Department of Pathology, Yeditepe University School of Medicine, Kayısdağı, Istanbul, Turkey
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  •  Accepted: 11 May 2009
  •  Published: 31 May 2009

Abstract

Thymic pathologies such as lymphoid follicular hyperplasia or thymoma are seen in 75% of myasthenia gravis subjects. Microscopic thymoma is a lesion that is seen in 15% of myasthenia gravis patients. The World Health Organization defines microscopic thymoma as a “ usually multifocal epithelial proliferation <1 mm in diameter”. Microthymoma, in other words microscopic-sized thymoma, should be considered in the differential diagnosis of microscopic timoma. We present the case of a 28-year-old male patient followed-up for myasthenia gravis and diagnosed with “microscopic thymoma” following thymectomy.

Key words: Thymus, microscopic thymoma, thymoma, myasthenia gravis.