International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 518

Full Length Research Paper

Cystatin C protection of human umbilical vein endothelial cell against oxidative stress injury through activating autophagy

Wenjing Fan
  • Wenjing Fan
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar
Wenyi Deng
  • Wenyi Deng
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar
Tingting Tang
  • Tingting Tang
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar
Yuning Zhu
  • Yuning Zhu
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar
Chi Zhang
  • Chi Zhang
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar
Zhisheng Jiang
  • Zhisheng Jiang
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar
Shunlin Qu
  • Shunlin Qu
  • Pathophysiology Department, Institute of Cardiovascular Disease and Key Lab for Arteriosclerology of Hunan Province, University of South China, Hengyang City, Hunan Province - 421001, PRC, China.
  • Google Scholar


  •  Received: 03 August 2018
  •  Accepted: 12 November 2018
  •  Published: 31 December 2018

References

Bengtsson E, Nilsson J, Jovinge S (2008). Cystatin C and cathepsins in cardiovascular disease. Frontiers Bioscience 13(3):5780-5786.
Crossref

 

Bengtsson E, To F, Grubb A, Håkansson K, Wittgren L, Nilsson J, Jovinge S (2005). Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice. Atherosclerosis 180(1):45-53.
Crossref

 

De Meyer GR, Martinet W (2009). Autophagy in the cardiovascular system. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793(9):1485-1495.

 

Devarajan P (2011). Biomarkers for the early detection of acute kidney injury. Current opinion in pediatrics 23(2):194.
Crossref

 

Ding Z, Wang X, Khaidakov M, Liu S, Dai Y, Mehta JL (2012). Degradation of heparan sulfate proteoglycans enhances oxidized-LDL-mediated autophagy and apoptosis in human endothelial cells. Biochemical and biophysical research communications 426(1):106-111.
Crossref

 

Huh CG, Håkansson K, Nathanson CM, Thorgeirsson UP, Jonsson N, Grubb A, Karlsson S (1999). Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene. Molecular Pathology 52(6):332.
Crossref

 

Lavandero S, Troncoso R, Rothermel BA, Martinet W, Sadoshima J, Hill JA (2013). Cardiovascular autophagy: concepts, controversies, and perspectives. Autophagy 9(10):1455-1466.
Crossref

 

Li W, Sultana N, Siraj N, Ward LJ, Pawlik M, Levy E, Yuan XM (2016). Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis. Journal of cellular and molecular medicine 20(9):1664-1672.
Crossref

 

Liu J, Sukhova GK, Sun JS, Xu WH, Libby P, Shi GP (2004). Lysosomal cysteine proteases in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 24(8):1359-1366.
Crossref

 

Mahmoudi MJ, Saboor-Yaraghi AA, Zabetian-Targhi F, Siassi F, Zarnani AH, Eshraghian MR, Mahmoudi M (2016). Vitamin A decreases cytotoxicity of oxidized low-density lipoprotein in patients with atherosclerosis. Immunological investigations 45(1):52-62.
Crossref

 

Rakkolainen I, Vuola J (2016). Plasma NGAL predicts early acute kidney injury no earlier than s-creatinine or cystatin C in severely burned patients. Burns 42(2):322-328.
Crossref

 

Sugimoto H, Makino M, Sawai H, Kawada N, Yoshizato K, Shiro Y (2004). Structural basis of human cytoglobin for ligand binding. Journal of Molecular Biology 339(4):873-885.
Crossref

 

Sukhova GK, Shi GP, Simon DI, Chapman HA, Libby P (1998). Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. The Journal of clinical investigation 102(3):576-583.
Crossref

 

Vandecasteele SJ, De Vriese AS (2013). cystatin C versus Creatinine for kidney function–based risk. The New England journal of medicine 369(25):2458-2459.

 

Wang F, Pan W, Wang H, Zhou Y, Wang S, Pan S (2014). The impacts of thyroid function on the diagnostic accuracy of cystatin C to detect acute kidney injury in ICU patients: a prospective, observational study. Critical Care 18(1):R9.
Crossref

 

Watanabe S, Hayakawa T, Wakasugi K, Yamanaka K (2014). Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity. Cell Death and Disease 5(10):e1497.
Crossref

 

Zhang YL, Cao YJ, Zhang X, Liu HH, Tong T, Xiao GD, Liu CF (2010). The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells. Biochemical and biophysical research communications 394(2):377-382.
Crossref