This study was planned to evaluate the liver function in patients with type 2 diabetes mellitus by measuring aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transpeptidase (GGT), total protein and albumin. The study was carried out in Wad Medani, Abo Agla Diabetes Centre. 50 patients with type 2 diabetes mellitus (23 male and 27 female) were included in the study. Their ages ranged between 43 and 79 years. Thirty matched normal individuals were taken as control group. In the present study, mean values of ALT, AST and GGT were significantly higher in patients than in the control (P<0.001). Total protein and albumin concentrations in patients were lower compared to control group (P<0.01). The mean of serum glucose in patients revealed significant difference (P<0.000) in comparison to the control group. Although the differences were statistically significant, the means of ALT, AST, GGT, total protein and albumin were falling within the normal range. Overall 11 patients (22%) had at least one or more abnormal liver function test enzymes.
Key words: Type 2 diabetes mellitus, hyperinsulinemia, liver function, metabolism, metabolic disorders, Sudanese.
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