International Journal of
Nutrition and Metabolism

  • Abbreviation: Int. J. Nutr. Metab.
  • Language: English
  • ISSN: 2141-2332
  • DOI: 10.5897/IJNAM
  • Start Year: 2009
  • Published Articles: 118

Full Length Research Paper

Antioxidative properties and inhibition of some pro-oxidant induced lipid peroxidation by aqueous extract of two species of eggplants Solanum macrocarpon and Solanum melongena

Ganiyu Oboh
  • Ganiyu Oboh
  • Department of Biochemistry, Federal University of Technology, Akure, Nigeria.
  • Google Scholar
Esther E. Nwanna
  • Esther E. Nwanna
  • Department of Biochemistry, Federal University of Technology, Akure, Nigeria.
  • Google Scholar
Emmanuel O. Ibukun
  • Emmanuel O. Ibukun
  • Department of Biochemistry, Federal University of Technology, Akure, Nigeria.
  • Google Scholar


  •  Accepted: 14 August 2013
  •  Published: 31 August 2013

Abstract

This study sought to determine the antioxidant activities and inhibitory effect of some egg plant species Solanum macrocarpon (yellow) and Solanum melongena (purple) on sodium nitroprusside and Fe2+ induced lipid peroxidation in rat’s pancreas. The totalphenolic, flavonoid and vitamin C content of the aqueous extracts were determined, as well as the antioxidant properties [ferric reducing antioxidant property (FRAP), Fe2+chelating ability and 2,2-Azinobis(3-ethylbenzo-thiazoline-6-sulfonate) (ABTS·),1,1-diphenyl-2picrylhydrazyl (DPPH) and hydroxyl (OH·) radicals scavenging ability] inhibitory effect of the extracts on sodium nitroprusside (SNP) and Fe2+-induced lipid peroxidation were also determined in vitro. The results revealed that there was no significant (> 0.05) difference in the total phenol, total flavonoid, vitamin C and FRAP of both eggplant, whileS. melongena had higher Fe2+ chelating ability and ABTS· scavenging ability. The aqueous extracts from S. macrocarpon and S. melongena inhibited SNP and Fe2+-induced lipid peroxidation in rat’s pancreas in a dose dependent manner. The antioxidant properties of the aqueous extracts from S. macrocarpon and S. melongena eggplant species and their strong inhibition of SNP and Fe2+-induced lipid peroxidation suggest that they could be a good antioxidants source in the management of degenerative diseases.

 

Key words: Solanum species, antioxidant properties, lipid peroxidation, degenerative diseases.