Journal of
AIDS and HIV Research

  • Abbreviation: J. AIDS HIV Res.
  • Language: English
  • ISSN: 2141-2359
  • DOI: 10.5897/JAHR
  • Start Year: 2009
  • Published Articles: 283

Full Length Research Paper

In-silico analysis of Mycobacterium leprae genome to find out potential drug targets

Asad Amir
  • Asad Amir
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Asif Siddiqui
  • Asif Siddiqui
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Anjali Malik
  • Anjali Malik
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Neeraj
  • Neeraj
  • Scientific and Applied Research Center, Meerut, Uttar Pradesh, India.
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Garima Dua
  • Garima Dua
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Garima Rastogi
  • Garima Rastogi
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Gayatri Sharma
  • Gayatri Sharma
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Richa Goel
  • Richa Goel
  • Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
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Singhal Gauvav
  • Singhal Gauvav
  • Scientific and Applied Research Center, Meerut, Uttar Pradesh, India.
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  •  Accepted: 29 September 2009
  •  Published: 30 November 2009

Abstract

Mycobacterium leprae is the causative agent of the disease, leprosy. In-silico analysis can be performed on M. leprae genome to find out the potential drug targets. This was done first by database search to find the recorded complete genes with complete sequences of M. leprae and then their comparative study with human by using homology searching using human BLAST. From a total of 1605 genes, potential drug targets have been identified.

 

Key words: Mycobacterium leprae GenomeBLAST, NCBI, drug target.