Journal of
AIDS and HIV Research

  • Abbreviation: J. AIDS HIV Res.
  • Language: English
  • ISSN: 2141-2359
  • DOI: 10.5897/JAHR
  • Start Year: 2009
  • Published Articles: 283

Full Length Research Paper

Highly active antiretroviral therapy (HAART) and body mass index (BMI) relationship in people living with HIV/AIDS (PLWHA) in the Federal Capital Territory, Nigeria and the neighbouring states

K. B. Mustapha
  • K. B. Mustapha
  • Department of Medicinal Chemistry and Quality Control, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria.
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T. S. Ehianeta
  • T. S. Ehianeta
  • Department of Pharmaceutical Technology and Raw Materials Development, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria.
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R. A. Kirim
  • R. A. Kirim
  • Department of Medicinal Chemistry and Quality Control, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria.
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F. T. Osungwu
  • F. T. Osungwu
  • National Institute for Pharmaceutical Research and Development Clinic, Abuja, Nigeria.
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D. K. Oladepo
  • D. K. Oladepo
  • Department of Microbiology and Biotechnology, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria.
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  •  Accepted: 25 January 2011
  •  Published: 31 March 2011

Abstract

This study was set to establish the relationship between highly active antiretroviral therapy (HAART) and body mass index (BMI) in people living with HIV/AIDS (PLWHA) in the Federal Capital Territory (FCT) and the neighbouring states within Nigeria- a representative data for sub-Sahara Africa. The study made use of 3 groupings: 44 healthy individuals, 79 HAART-treated HIV (human immuno deficiency syndrome) infected individuals and 21 non-HAART treated HIV-infected individuals from a pool of 402 subjects and age, weight and height were documented and statistically analyzed (Graph Pad, Prism 3). The result showed that significant weight loss was typified by low BMI values (<20) presented in non-HAART HIV-infected subjects. The trend of BMI cum weight loss in HIV infected subjects follows the order: non-HAART PLWHA > HAART treated PLWHA > healthy subjects. It was found that weight loss and consequently low BMI is not gender-dependent in HAART and non-HAART subjects.

 

Key words: Body mass index (BMI), highly active antiretroviral therapy (HAART), people living with HIV/AIDS (PLWHA).